polycythaemia


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pol·y·cy·the·mi·a

(pol'ē-sī-thē'mē-ă)
An abnormal increase in the number of red blood cells.
Synonym(s): erythrocythemia, polycythaemia.
[poly- + G. kytos, cell, + haima, blood]

polycythaemia

An abnormal increase in the number of red blood cells as a result of increased red cell production by the bone marrow. This occurs naturally in people living at high altitudes (secondary polycythaemia) but may occur for no apparent reason (polycythaemia vera) causing flushed skin, headaches, high blood pressure (HYPERTENSION) and blurred vision. STROKE is a common complication. Treatment is by regular bloodletting (venesection) sometimes supplemented by the use of anticancer drugs or radioactive phosphorus. An American study reports that low-dose aspirin can safely prevent thrombotic complications in people with this disease. A gene for polycythaemia vera was reported in 1998.

polycythaemia

greater than normal number of red blood cells (RBC) per unit volume of blood. A compensatory mechanism in hypoxia (arising either from lung disease or in healthy people at altitude) which leads to stimulation of RBC production in the bone marrow. Improves oxygen transport, but at the expense of increasing blood viscosity, adding to the resistance to blood flow in the circulation. See also erythropoiesis.

pol·y·cy·the·mi·a

(pol'ē-sī-thē'mē-ă)
An abnormal increase in the number of red blood cells.
Synonym(s): erythrocythemia, polycythaemia.
[poly- + G. kytos, cell, + haima, blood]
References in periodicals archive ?
Among the haematological abnormalities, polycythaemia was the most common, presenting in 14 (56%) neonates (Table 5).
Results: In a total of 40 patients were diagnosed as primary polycythaemia or polycythaemia Vera (PRV).
A new polycythaemia veraassociated SOCS3 SH2 mutant (SOCS3F136L) cannot regulate erythropoietin responses.
Results: Out of the 93 myeloproliferative neoplasm (MPN) patients, 33(35%) had polycythaemia vera, 36(39%) had essential thrombocythaemia and 24(26%) had idiopathic myelofibrosis.
Epidemiology of the myeloproliferative disorders: essential thrombocythemia, polycythaemia vera and idiopathic myelofibrosis.
A unique clonal JAK2 mutation leading to constitutive signaling causes polycythaemia vera.
I would say I am relatively healthy considering my age, my former poor lifestyle and the fact that I have polycythaemia (overproduction of red blood cells), which is ng treated by chemotherapy.
Acute leukaemia after hydroxyurea therapy in polycythaemia vera and allied disorders: prospective study of efficacy and leukaemogenicity with therapeutic implications.
Additional documented risk factors include sepsis, perinatal hypoxia, dehydration, maternal diabetes and polycythaemia in neonates, and congenital heart disease, cancer, chemotherapy, protein-losing states, total parenteral nutrition (TPN) and trauma/surgery in children.
Small for gestational age babies: aspiration syndrome, hypocalcaemia, hypoglycaemia, hypothermia, perinatal asphyxia, polycythaemia.
The pulmonary function test abnormalities commonly encountered in CTD Lung volumes DLCO Increased Asthma, emphysema, Pulmonary haemorrhage bronchiectasis and syndromes, bronchiolitis obliterans polycythaemia Decreased Interstitial pneumonia Interstitial pneumonia (ILD) (ILD) BOOP PTED Pleural and thoracic cage disease
The physiological anaemia normally seen in pregnancy is exacerbated in the obese patient by increased activity of the renin-angiotensin system, but partially offset by secondary polycythaemia (24).