polycystic


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polycystic

 [pol″e-sis´tik]
containing many cysts.
polycystic kidney disease either of two unrelated hereditary diseases in which there is massive enlargement of the kidney with cyst formation. It occurs in two forms, distinguished by age of onset and other characteristics.

Autosomal dominant polycystic kidney disease (ADPKD, formerly called adult polycystic kidney disease) is the most common type of cystic disease of the kidneys. It is usually manifested during the third decade of life. Renal failure may appear by the fifth decade, with terminal failure occurring in the next ten years, although in some cases it never appears. Although there is rarely any liver dysfunction accompanying this disorder, cyst formation in the liver does occur.

Autosomal recessive polycystic kidney disease (ARPKD), formerly called childhood polycystic kidney disease, is diagnosed at birth or in the first ten years of life and is much less common than the autosomal dominant form. Both the kidney and the liver are involved, causing renal failure and liver failure with portal hypertension. Characteristic symptoms early in the process include pain, hematuria, urinary tract infection, kidney stones, and obstructive uropathy with anuria.

Treatment of both types of polycystic kidney disease is largely symptomatic. Renal dialysis and kidney transplantation during end-stage renal disease can prolong life but offer no cure. Families with histories of polycystic kidney disease require genetic counseling and may need help in coping with the prospect of future offspring afflicted with the disease.
polycystic ovary syndrome (PCOS) a clinical symptom complex associated with polycystic ovaries and characterized by oligomenorrhea or amenorrhea, anovulation (hence infertility), and hirsutism. Both hyperestrogenism (from peripheral conversion of androgen) and hyperandrogenism are present. Excretion of follicle-stimulating hormone and 17-ketosteroids is normal, but infertility is usually persistent, requiring treatment with wedge resection, clomiphene, or gonadotropins. Called also Stein-Leventhal syndrome.
polycystic renal disease polycystic kidney disease.

pol·y·cys·tic

(pol'ē-sis'tik),
Composed of many cysts.

polycystic

(pŏl′ē-sĭs′tĭk)
adj.
Having or containing many cysts: polycystic kidney disease.

pol·y·cys·tic

(pol'ē-sis'tik)
Composed of many cysts.
References in periodicals archive ?
Oligo and/or anovulation, excess androgen activity and/or polycystic ovarian morphology on ultrasound.
Table 1 Prevalence of cutaneous manifestations in patients with polycystic ovarian syndrome (n=50).
Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study.
Determinants of impaired fasting glucose versus glucose intolerance in polycystic ovary syndrome.
However, it remains uncertain whether these biomarkers could distinguish polycystic ovary syndrome from other metabolic diseases or divide polycystic ovary syndrome into subgroups.
Androgen excess and polycystic ovary syndrome society (AE-PCOS) task force analyzed pertinent literature from 1985 to 2012, eliciting data from 1285 women and controls.
Polycystic ovary syndrome is the most common endocrine disorder in females of reproductive age with a prevalence of up to 20%.
ADPKD is the most common form of polycystic kidney disease (PKD), which is one of the most common, life-threatening genetic diseases affecting thousands in America and millions worldwide.
The ovaries are usually enlarged with multiple follicles, or small cysts, hence the description polycystic ovaries.
Polycystic ovarian syndrome (PCOS) is a gynecological disorder affecting 5-10% women of reproductive age [1, 2].

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