Comparison of the moisturization efficacy of two vaginal moisturizers: Pectin versus polycarbophil
compared with placebo in irritable bowel syndrome.
Junginger, Effects of the mucoadhesive polymer polycarbophil
on the intestinal absorption of a peptide drug in the rat, J.
There are seven types of products that act as laxatives: saline (phosphates and magnesium hydroxide and its salts), stimulants/irritants (cascara, bisacody1, casanthranol, senna, and castor oil), bulking agents (methylcellulose, polycarbophil
, and psyllium), emollient (mineral oil), fecal softeners (docusate), hyperosmotics (glycerin, lactulose), and tegaserod (Zelnorm).
Pharmacologic Treatment of Constipation in Elders Stimulant Laxatives Senna/Cascara (Ex-Lax[R], Senokot[R], Nature's Remedy[R]) Oral bisacodyl (Dulcolax[R]) Phenolphthalein and castor oil (not recommended in elders due to side effects of malabsorption and dehydration) Bulk Laxatives Psyllium (Metamucil[R], Perdiem[R]) Methylcellulose (Citrucel[R]) Polycarbophil
(FiberCon[R]) Osmotic Laxatives Magnesium hydroxide (Milk of Magnesia[R]) Magnesium citrate Sodium phosphate Lactulose Polyethylene glycol (MiraLax[R]) Glycerine Sorbitol Fecal Softeners Docusate sodium (Colace[R]) Mineral oil Enemas Phosphate Soap suds Tap water Oil retention Table 5.
Equalactin, for irritable bowel syndrome, contains calcium polycarbophil
, a bulk-forming fiber that helps absorb water in the intestinal tract.
Realizing that calcium polycarbophil
(Mitrolan/FiberCon) is a bulk laxative that can be used to regulate bowel function, whether constipation or diarrhea, but only when fluid intake is sufficient, and not when incontinence is a problem.
You can recommend that patients gradually increase fiber intake over several weeks to a total of 20 g/d to 25 g/d) (18) through fiber-rich foods (vegetables leg, carrots, broccoli, string beans], fruits [eg, peaches, apples, oranges], whole-grain breads, pasta, cereal, etc) (SOR: C) or bulk supplements (eg, psyllium, methylcellulose, and polycarbophil
) (SOR: B).
Physician recommendations are now driving sales of Konsyl's new fiber tablets made with calcium polycarbophil
. The formulation is the same as Lederle Laboratories' best-selling Fibercon, says Steiber, and at a 30% savings.
Regarding treatment: of the bulking agents, psyllium increases stool frequency but data are insufficient regarding calcium polycarbophil
, methylcellulose, or bran.
The caplets are designed to restore water balance in the colon through calcium polycarbophil
, the active ingredient.
Bulking agents, such as natural and synthetic fiber (bran, psyllium, methylcellulose, and calcium polycarbophil
), draw water into the intestine, increase stool weight, and soften stool consistency.