polyangiitis


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polyangiitis

 [pol″e-an″je-i´tis]
inflammation involving multiple blood or lymph vessels.

pol·y·an·gi·i·tis

(pol'ē-an'jē-ī'tis),
Inflammation of multiple blood vessels involving more than one type of vessel, for example, arteries and veins, or arterioles and capillaries.

microscopic polyangiitis

A systemic small-vessel vasculitis that primarily affects the kidneys, skin, and lungs of middle-aged men.

Clinical findings
Fever, malaise, myalgia, weight loss, and autoimmunity, including antineutrophil cytoplasmic antibodies (p-ANCA). Skin lesions occur in 30 to 50%, usually presenting as purpura due to leukocytoclastic vasculitis, less commonly as nodules involving the vessels of the dermis and subcutaneous fat and ulcers. The kidney shows rapidly progressive focal and segmental glomerulonephritis.

DiffDx
Polyarteritis nodosa.

pol·y·an·gi·i·tis

(pol'ē-an'jē-ī'tis)
Inflammation of many blood vessels involving more than one type of vessel, e.g., arteries and veins, or arterioles and capillaries.

pol·y·an·gi·i·tis

(pol'ē-an'jē-ī'tis)
Inflammation of multiple blood vessels involving more than one type of vessel.
References in periodicals archive ?
The "Microscopic Polyangiitis (MPA) - Pipeline Review, H1 2019" drug pipelines has been added to ResearchAndMarkets.com's offering.
(10) There is a clear absence, however, of systemic diseases such as granulomatosis with polyangiitis, Churg-Strauss syndrome, sarcoidosis, Sjogren syndrome, and infectious granulomatosis.
Imaging features suggested the possibility of a primary lung malignancy, organising pneumonia, granulomatosis with polyangiitis, sarcoidosis or lymphoma.
Performance evaluation of three assays for the detection of PR3-ANCA in granulomatosis with polyangiitis in daily practice.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is referred as a subgroup of small vessel vasculitis characterized by immune depositions and the presence of ANCAs and includes microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic GPA (EGPA).
Erich Kiehl stepped up to help Spencer, who was traveling to Cleveland to get treatment for eosinophilic granulomatosis with polyangiitis (EGPA), a rare autoimmune disease that causes inflammation in a person's blood vessels. 
Eosinophilic granulomatosis with polyangiitis or Churg--Strauss syndrome (CSS) is a systemic vasculitis characterized by bronchial asthma, hypereosinophilia, and systemic vasculitis.
It is seen in PAN, microscopic polyangiitis, Wegener's granulomatosis, Churg-Strauss syndrome, and secondary vasculitis due to rheumatoid arthritis or Sjogren's syndrome.
(2) showed that serum-induced fibroblast proliferation in vitro was highly increased in microscopic polyangiitis with pulmonary fibrosis compared to that without it, probably through oxidative stress, suggesting the potential of MPO-ANCA to trigger the fibrotic process.
Different characteristics were compared between the three groups of AAV; GPA (Granulomatosis with polyangiitis), MPA (Microscopic polyangiitis) and EGPA (Eosinophilic granulomatosis with polyangiitis).
Rituximab is indicated for non-Hodgkin's lymphoma (NHL), chronic lymphocytic leukemia (CLL; in combination with chemotherapy), rheumatoid arthritis (RA; in combination with methotrexate), and granulomatosis with polyangiitis and microscopic polyangiitis (in combination with glucocorticoids) [20, 21].