(29,30) Genotyping has numerous advantages, including not being affected by immunoglobulin coating of the RBCs, by the presence of recently transfused RBCs, or by any form of polyagglutination
. (30) High-throughput genotyping methods can be applied to both patients and blood donors, resulting in the possibility of providing genotype-matched, rather than just ABO/RhD-matched or crossmatch-compatible, RBCs.
A Prolonged storage at room temperature can result in bacterial proliferation with hemolysis and a tendency toward polyagglutination
, is, therefore, not recommended.