polyadenylation


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pol·y·ad·e·nyl·a·tion

(pol'ē-ad'ĕ-nil-ā'shŭn),
1. The process of formation of poly(adenylic acid).
2. The covalent modification of a macromolecule (for example, mRNA) by the formation of a polyadenylyl moiety covalently linked to the macromolecule.

polyadenylation

The process by which a sequence of polyadenylic acids (adenosine ribonucleotides) is added to the end of a spliced RNA after its transcription from DNA, resulting in mature mRNA. This addition on the RNA molecule is sometimes referred to as a poly-A tail, and commonly contains several-hundred bases.

polyadenylation

addition of a sequence of ADENINE NUCLEOTIDES to the 3′-end of most eukaryotic RNA molecules, after their TRANSCRIPTION. The sequence is often called a.poly(A) tail.
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References in periodicals archive ?
Specificity factors in cytoplasmic polyadenylation. Wiley Interdiscip Rev RNA 2013;4(4):437-461.
Primers used for PCR amplifications are given in Tables 1, 2, and 3 for the peregrine falcon, the snowy owl, and the blue-fronted Amazon parrot, respectively, and include the generic polyA primers used to identify the site of 3-prime polyadenylation. All primers were purchased from ThermoFisher oligo services (ThermoFisher Scientific, Waltham, MA, USA).
Indeed, TTSa-RNAs have been described as AGO1/2-associated, miRNA-(22-24 nt) sized sRNAs whose 3' ends aligned with the annotated polyadenylation sites and mapping on the sense strand [15].
Histone modification refers to the process of histone methylation, acetylation, phosphorylation, polyadenylation, ubiquitination, and ADP glycosylation under the action of related enzymes.
Takeuchi et al., "Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex," Molecular Cell, vol.
Mitochondrial mRNA stability and polyadenylation during anoxia-induced quiescence in the brine shrimp Artemia franciscana.
The cDNA sequence contained a stop codon (TGA) at position 805-807 bp and a polyadenylation signal (AATAAA) located 12 bp upstream of the poly (A) tail (Fig.
Alternative polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR.
Alternative polyadenylation (APA) has been emerged as an important mechanism for posttranscriptional regulation of genes in eukaryotes [1].
Manley, "Mechanisms and consequences of alternative polyadenylation," Molecular Cell, vol.