National coverage levels for the third dose of
poliovirus vaccine (Pol3) delivered through routine immunization services by age 12 months have been <60% since 2002, * with lower rates in northern states.
Current Advisory Committee on Immunization Practices (ACIP) recommendations specify 4 doses of trivalent inactivated
poliovirus vaccine (IPV) at ages 2 months, 4 months, 6-18 months, and 4-6 years.
Vaccination;
poliovirus vaccine; immunization schedule; child welfare.
In 2017, a total of 172 SIAs were conducted in five World Health Organization (WHO) regions, during which nearly 1.8 billion total OPV and inactivated
poliovirus vaccine (IPV) doses were allocated for use; 161 SIAs were conducted in 2018, with approximately 1.7 billion bOPV and IPV doses.
A global, synchronized switch to bivalent oral
poliovirus vaccine (bOPV, types 1 and 3 only) was completed in April 2016.
IPV is the only
poliovirus vaccine recommended for immunocompromised persons and their household contacts.
This progress has been achieved through widespread use of oral
poliovirus vaccine (OPV), most commonly trivalent OPV (tOPV), which contains types 1, 2, and 3 live, attenuated polioviruses.
The cost of Pediarix is currently 4%-5% above the combined cost of DTaP, hepatitis B (recombinant), and inactivated
poliovirus vaccines, said Dr.
Protective efficacy of a monovalent oral type 1
poliovirus vaccine: a case-control study.
A resurgence in wild poliovirus (WPV) transmission occurred in Nigeria during 2003-2004 after a loss of public confidence in oral
poliovirus vaccine (OPV) and suspension of supplementary immunization activities (SIAs) * in several northern states (1).
In January 1997, the Food and Drug Administration (FDA) approved an amendment to the package labeling for the inactivated
poliovirus vaccine (IPV) currently licensed in the United States, allowing the third dose of this IPV in an all-IPV schedule to be administered as early as age 6 months.
In addition,
poliovirus vaccine has been offered to members of all unvaccinated communities.
