polar body biopsy

polar body biopsy

Reproductive medicine The removal of the polar body, the genetic residua from the oocyte after the 1st meiotic division, which is metabolically inactive, and a mirror image of the oocyte, which can be removed with impunity. See Assisted reproduction, Blastocyst biopsy, Cleavage stage biopsy.
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Polar body biopsy is the removal of one or both polar bodies, independently or simultaneously.
These aneuploidies can be identified by polar body biopsy; however most aneuploidies appear due to improper separation of sister chromatids after meiosis II, so that polar body biopsy will not detect them [30].
This system must be suitable for the implementation of ICSI, and other treatments, such as polar body biopsy, Trophektodermbiopsie, laser-assisted hatching.
[1.] A variety of techniques may be employed in preimplantation diagnosis, including embryo analysis, trophectoderm biopsy, and polar body biopsy. For discussion, see Yury Verlinsky, Eugene Pergament, and Charles H.