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physician office laboratory

A diagnostic lab in a physician’s office with an abbreviated menu of tests that can be performed while the patient is in the office, so the physician can better manage the patient.

HIV-1 gene

Any of the genes present in the human immunodeficiency virus. See AIDS.
HIV genes
art/trs gene rev gene, see there.
env gene Encodes viral coat proteins gp 120 and gp 41, which mediate CD4 binding and membrane fusion, controlled by tat and rev
gag gene Encodes nucleocapsid core proteins including p24
nef gene 3´ orf, B gene, ORF-2 gene Encodes a protein of unknown function found in infected Pts that may down-regulate viral expression–nef deletion results in a five-fold increase in viral DNA synthesis and replication
pol gene Encodes reverse transcriptase, protease, integrase and ribonuclease
R gene Encodes TAR–transcription activating response element, which has a nonspecific immunodeficiency effect
rev gene art/trs gene Encodes a 19 kD post-transcriptional protein regulator required for HIV replication, up-regulating HIV synthesis by transactivating anti-repression, ↑ levels of envelope RNA by regulating the env gene; inactivation of rev prevents viral replication–as measured by the successful production of the p24 glycoprotein by infected monocytes can be massively ↑ by adding cytokines to culture medium
tat gene Encodes a potent 14 kD transcription activator that amplifies HIV replication, the inactivation prevents viral replication
vif gene Facilitates infectivity of free HIV
vpr gene Encodes a weak transcription activator
vpu gene Unique to HIV-1, encodes a 16 kD product which, when mutated, has a 5-10-fold Ø in replicative capacity and is critical for efficient budding of virions NEJM 1991; 324:308rv
†Gene encoding regulatory protein
‡Gene encoding structural protein

POL

Abbreviation for physician office laboratory.

pol

A viral gene which, in retroviruses, acts in conjunction with the gag gene to direct the formation of gag-pol messenger RNAs.
References in periodicals archive ?
They highlighted that the government has imposed many taxes on POL products as it was receiving 27.5 percent GST on HSD and 17 percent GST on other POL products.
Pol Pot, born Saloth Sar in 1925, was the son of relatively well-off rice farmers.
Maybe at the end of the trip he can do bigger class but not the big Grand Prix now," said van de Pol.
People in Sar Pol Zahab city rushed to the streets in fear and were in open areas due to the strong after-shakes, local reports said.
Pol Pot became leader of Cambodia in 1975 when the Khmer Rouge captured the capital, Phnom Penh.
Melson likens POL technology (also referred to as a Passive Optical Network, or PON) to a FIOS-type architecture routed throughout a building or enterprise campus, rather than a residential neighborhood.
The PS95 a head "Dinner with Champagne Pol Roger" will include a four-course meal featuring wild garlic risotto served with Pol Roger Pure NV; confit salmon with garden herbs accompanied by Pol Roger Vintage Rose 2004; spring lamb cutlet, lamb navarin, minted fresh peas and fondant potato with Pol Roger Cuvee Sir Winston Churchill 2000, and garden rhubarb Pavlova and vanilla ice cream complemented by Pol Roger Rich NV.
Clr Andrew Pinnock said at the Heavy Woollen Planning Sub-Committee: "It's POL site and we don't have much choice but to approve, but I want to see a condition that there should be an entrance to the rest of the site.
For this purpose, we used primer extension assays to measure extension of primers that had an Oz:G, Oz:A, Oz:C, or Oz:T base pair at the primer terminus/extension site; we used each of the three polymerases (Pol [beta], KF [exo.sup.-], and Pol [beta]) in these assays to assess consistency of our findings.
In this paper, the chaotic motions of the Duffing-Van der Pol oscillator with external and parametric excitations are studied analytically with the Melnikov method.
His jailer Non Nou said yesterday that Pol Pot's heart stopped at 11.15pm (17.15 BST) on Wednesday night in an area of northern Cambodia about a mile from the Thai border.
If Pol Pol was half as smart as we thought he was, he would have realised that his mandate was to conclude that the comrade was in no way responsible for the blast, because he knew nothing.