podophyllotoxin derivatives

podophyllotoxin derivatives

Drugs used to treat cancer. An example is etoposide (Etopophos, Vepesid).
References in periodicals archive ?
Etoposide and other podophyllotoxin derivatives are used from their antineoplastic or antimitotic properties, they affect the nervous and gastro-intestinal systems.
Etopside and other podophyllotoxin derivatives produced a central depressant effect with locomotor alterations (Dobb and Edis, 1984; Ascher and Delaney, 1988).
These methods have yielded important discoveries including vincristine, vinblastine, the podophyllotoxin derivatives, lO-hydroxy-camptothecin and Taxol (Suffness and Douors, 1979; Wani et al.