podophyllin


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resin

 [rez´in]
1. a solid or semisolid organic substance exuded by plants or by insects feeding on plants, or produced synthetically; they are insoluble in water but mostly soluble in alcohol or ether. adj., adj res´inous.
2. a compound made by condensation or polymerization of low-molecular-weight organic compounds.
acrylic r's products of the polymerization of acrylic or methacrylic acid or their derivatives, used in fabrication of medical prostheses and dental restorations and appliances.
anion exchange resin see ion-exchange resin.
cation exchange resin see ion-exchange resin.
cholestyramine resin a synthetic, strongly basic anion exchange resin in the chloride form which chelates bile salts in the intestine, thus preventing their reabsorption; used as an adjunctive therapy to diet in management of certain hypercholesterolemias and in the symptomatic relief of pruritus associated with bile stasis.
composite resin a synthetic resin, usually acrylic based, to which a high percentage of ceramic reinforcing filler has been added, such as particles of glass or silica coated with a coupling agent to bind them to the matrix; used chiefly in dental restorations. Called also composite.
epoxy resin a tough, chemically resistant, adhesive, flexible, dimensionally stable resin of epoxy polymers; used as denture base material.
ion exchange resin a high-molecular-weight insoluble polymer of simple organic compounds capable of exchanging its attached ions for other ions in the surrounding medium; classified as (a)cation or anion exchange resins, depending on which ions the resin exchanges; and (b) carboxylic, sulfonic, and so on depending on the nature of the active groups.
podophyllum resin a mixture of resins from podophyllum, used as a topical caustic in treatment of laryngeal papillomas, condylomata acuminata, and other epitheliomas.

pod·o·phyl·lum res·in

a resin extracted from the dried roots and rhizomes of Podophyllum peltatum, a perennial herb common in moist, shady situations in the eastern parts of Canada and the U.S. The drug has been used by Native Americans and members of First Nations as a vermifuge and emetic. The chief constituents of the resin belong to the group of lignins; the most important ones present in podophyllum resin are podophyllotoxin (about 20%), β-peltatin (about 10%), and α-peltatin (about 5%). All three occur both free and as glucosides. The resin was used as a purgative but has been replaced by milder agents. It is cytotoxic and used as a paint in the treatment of genital and other warts.

podophyllin

(pŏd′ə-fĭl′ĭn)
n.
A bitter-tasting resin obtained from the dried root of the mayapple and used in medicine as a caustic.
References in periodicals archive ?
Hence, the difference obtained was statistically significant and podophyllin 20% is better treatment of genital warts than imiquimod 5%.
Podophyllin has both local and systemic effects associated with topical and oral use.
Role of podophyllin resin therapy in oral hairy leukoplakia in HIV infection: Clinicopathologic study.
The outcome of most of the children with domestic accidents in our study were non-fatal (96.8%) but 1% resulted in death and 1% had hypoxic ischemic sequelae secondary to podophyllin poisoning.
Currently many modalities like curettage cryotherapy pricking with sterile needle photodynamic therapy laser salicylic acid glycolic acid tretinoin podophyllin cantharidin trichloroacetic acid silver nitrate are available.1
Decoction of roots is used to cure liver problems [27] and hepatic diseases [13] Fruits are edible [15], diarrhoea [13, 44-46], blood diarrhoea [34, 47], chronic constipation [14], anticancer [17] and they constitute a compound called, podophyllin, which is commonly used as a purgative; podophyllotoxin is the active principle.
Podophyllum peltatum Podophyllin resin Panaxquinquefolium Ginsenosides, protopanaxadiol, commercially available for relief of colds and flu.
Treatments that can be done without anesthesia (cryotherapy, podophyllin, trior bichloracetic acid, and 5-fluorouracil) will lead to complete clearance in two-thirds of patients, he estimated.
Electrosurgery, excision, laser therapy (all requiring anesthesia) can have a 100% response rate, while cryotherapy, podophyllin, tri- or bichloracetic acid, and 5-fluorouracil (without anesthesia) will lead to complete clearance in two-thirds of patients.
Treatments that can be done without anesthesia (cryotherapy, podophyllin, trior bichloracetic acid, and 5-fluorouracil) lead to complete clearance in two-thirds of patients.
* Podophyllin resin 10% to 25% in a compound tincture of benzoin.
Podofilox is the active compound in podophyllin resin.