podocyte


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podocyte

 [pod´o-sīt]
an epithelial cell of the visceral layer of a renal glomerulus, having a number of footlike radiating processes (pedicles).

pod·o·cyte

(pod'ō-sīt),
The modified epithelial cell of the visceral layer of glomerular capsule in the renal corpuscle, attached to the outer surface of the glomerular capillary basement membrane by cytoplasmic foot processes (pedicels); believed to play a role in the ultrafiltration of blood.
[podo- + G. kytos, a hollow (cell)]

podocyte

/podo·cyte/ (pod´ah-sīt) an epithelial cell of the visceral layer of a renal glomerulus, having a number of footlike radiating processes (pedicels).

pod·o·cyte

(pod'ō-sīt)
An epithelial cell of the visceral layer of Bowman capsule in the renal corpuscle, attached to the outer surface of the glomerular capillary basement membrane by cytoplasmic foot processes (pedicels); believed to play a role in the ultrafiltration of blood.
[podo- + G. kytos, a hollow (cell)]

podocyte

an epithelial cell of the visceral layer of a renal glomerulus, having a number of footlike radiating processes (pedicles).
References in periodicals archive ?
By inhibiting calcineurin, it blocks IL-2 expression and T-cell mediated immune responses, and stabilizes the podocyte in the kidney.
WT-1 gene mainly expresses in the progenitor cells of cap-stage mesenchymal and pronephric tubule aggregate during early metanephros development and then it will be confined to podocyte.
142) PLA2R1 has recently attracted attention as a major autoantigen in membranous nephropathy, a severe autoimmune disease leading to podocyte injury and proteinuria, (143) although it is not clear whether this role of PLA2R1 is s[PLA.
Sharma K: The link between obesity and albuminuria: adiponectin and podocyte dysfunction.
With progression of the disease, there is fusion of podocyte foot processes in association with increasing proteinuria.
Revisit complement-related innate immunity by NGS sequencing of 18 complement regulatory protein genes in search of variants which may account for disease heterogeneity, by blocking C5b-9 formation with recombinant factor H in 2 murine models of MN, and by searching for C5b-9 antagonists by high-throughput screening of chemical libraries in podocyte cell-based assays.
Allopurinol also improved podocyte injury and albuminuria in fructose-induced metabolic syndrome in rats (Wang et al.
Increase in glomerular size, thickening of the glomerular basement membrane (GBM), mesangial expansion and widening of podocyte foot processes are the characteristics of early diabetic changes7.
2-4) Glomerular podocyte injury causes proteinuria and results in tubular and interstitial injury.
These metabolic studies demonstrate how the ATeam sensors can provide important insight into podocyte cell biology, potentially advancing our understanding of the role of metabolic dysfunction in chronic kidney diseases (Ozawa et al.