In the 13th century, Randolphus of Bocking from Chichester made use for the first time of the term "gout" in order to define podagra
, the designation being derived from the Latin word gutta (drop), on the assumption that the excess of one of the four humours might drip off, under particular circumstances, in one joint and trigger the symptoms.
Older people with arthritis signs and symptoms Signs/Symptoms Frequency Percentage pain 34 100 Swelling 4 12 Numbness 26 76 Redness 1 3 podagra
(swelling of the big toe) 3 9 tophi (formation of nodules in between joint) 5 15 Immobility 2 6 Deformity 6 18 Fever 0 0 Table 4.
84, 'De Podagra
' <http://www.bibliotecaitaliana.it/xtf/ view?docId=bibit000299/bibit000299.xml>.
 Lucian's satires were much in demand with Latin editions in 1515, 1517, 1518, 1519, and 1530,  a German version in 1512,  and Lucian's Podagra
Laus (In praise of gout), as translated by Pirckheimer, published in 1529.
For many people, gout initially affects the joints in the big toe, a condition called podagra
. Sometime during the course of the disease, gout will affect the big toe in about 75 percent of patients.
20, after a long list of botanical drugs for podagra
, he remarks: "Or take the fat of a vulture, mix it with some sheep's dung, and put it on the place; when one pounds the fat of a he-goat and kneads it with the dung of a sheep and with some saffron and puts it on the podagra
, it will dissolve its pain, God willing." Al-Tabari, op.
1500-1540) observed that drunkards could expect a "bad, untimely old age; stupid, dull head; vertigo, trembling of the hands; podagra
; dropsy; and as the saying goes, |water on the brain,'" in addition to liquid oily legs," quite possibly the edema of the legs associated with alcoholic cardia beriberi.(48) For his part, Ulrich Zwingli (1484-1531) warned against premature old age, noting that "those who are accustomed to excess of wine will inevitably succumb at length to some dangerous sickness, epilepsy, paralysis, dropsy, elephantiasis and the like."(49) And from the mid-16th century we have the testimony of the Italian Alvise or Luigi Cornaro (1475-1566), perhaps the first recovering alcoholic on record.
For example, podagra
, an inflammation of the big toe which is the most common symptom of gout in younger people, is fairly rare in older patients - particularly women.
The ability of the rule to differentiate between gout and septic arthritis was tested retrospectively in 33 patients with acute gout (podagra
excluded) diagnosed by the presence of monosodium urate joint crystals and 27 patients with septic arthritis diagnosed by positive bacterial culture.