pneumocyte


Also found in: Wikipedia.

al·ve·o·lar cell

any of the cells lining the alveoli of the lung, including the squamous alveolar cells, the great alveolar cells, and the alveolar macrophages.
Synonym(s): pneumocyte

pneumocyte

(nū′mō-sīt)
Either of the two types of cells that form the alveoli of the lung. Type I cells are simple squamous epithelium that permit gas exchange. Type II cells are rounded and produce surfactant.
References in periodicals archive ?
A severe inflammatory reaction that ultimately results in both endothelial and pneumocyte damage leads to the observed severe hypoxaemia.
Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP).
Lamellar bodies are secreted by the type II pneumocyte and unfold to form tubular myelin and other large aggregates that are absorbed onto the hydrated inner layer of the alveoli.
Multifocal micronodular pneumocyte hyperplasia is rarely encountered.
Endogenous surfactants, those which occur naturally in the lungs of the baby, are a product of the alveolar type II cell, the granular pneumocyte, and that natural surfactant consists of 85 to 90 percent lipids and 10 percent proteins, jointly comprising surfactant as we know it, dipalmitoylphosphatidylcholine (DPPC), or lecithin.
Fas/Fas ligand pathway is involved in the resolution of type II pneumocyte hyperplasia after acute lung injury: evidence from a rat model.
(52) In some instances, tumors that metastasize or grow in the interstitium, including squamous cell carcinoma, can induce a pneumocyte reaction that can be sufficiently atypical as to raise a concern for lepidic pattern adenocarcinoma (Figure 4, C).
Histologic analysis showed that lesions were similar to those observed in humans and indicated necrotizing bronchointerstitial pneumonia with type II pneumocyte hyperplasia, abundant fibrin, and streaming mucus in airways.
Moreover, mild acute and/or chronic inflammation, type 2 pneumocyte hyperplasia, and alveolar extension are also seen in the slide.
At the periphery of the mycotic lesions were foci of type II pneumocyte hyperplasia, septal fibroplasia, and mononuclear infiltration.
Secretion of mucus proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines.
They also suggested KL-6 was a sensitive indicator of type II pneumocyte damage, increased permeability of the air-blood barrier, and destruction of the healthy lung parenchyma.