Also found in: Encyclopedia.
rep·li·ca·tive form (RF),
1. an intermediate stage in the replication of either DNA or RNA viral genomes that is usually double stranded;
2. the altered, double-stranded form to which single-stranded coliphage DNA is converted after infection of a susceptible bacterium, formation of the complementary ("minus") strand being mediated by enzymes that were present in the bacterium before entrance of the viral ("plus") strand.
Farlex Partner Medical Dictionary © Farlex 2012
plus strandThe strand of a nucleic acid (often viral RNA, but also any strand of DNA or RNA with equivalent sequence), often of bacteriophage origin, used as a template for producing a complementary (minus) strand of RNA; together, the plus and minus strands form double-stranded RNA, the replicative form of the virus.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.