The ability to create them from self-renewing pluripotent stem cells using the UCLA technique could lead to new approaches to cancer immunotherapy and could spur further research on T cell therapies for viral infections such as HIV, and autoimmune diseases.
In the opinion of the AG, inventions relating to pluripotent stem cells can only be patentable if they are obtained without detriment to the embryo, be that an embryo's destruction, modification or use as a base material.
Kevin D'Amour, PhD, vice president of Research and chief scientific officer for ViaCyte, said, 'The universal donor pluripotent stem cell line will represent a tremendous asset to ViaCyte, and the regenerative medicine field in general, and we are grateful to CIRM for their continued support to advance this new approach.
Researchers from the Massachusetts General Hospital Center for Regenerative Medicine (MGH-CRM) and the Harvard Stem Cell Institute have a developed a new type of human pluripotent stem cell that can be manipulated more readily than currently available stem cells.
"Induced pluripotent stem cells represent a huge opportunity for science and medicine, but to truly and effectively use them we need to more completely understand their mutational burden," said senior author Kelly A.