1 Introduction to
Pluripotent Stem Cells: Biology and Applications
BioTime is a clinical-stage biotechnology company focused on developing and commercializing novel therapies developed from what the company believes to be the world's premier collection of
pluripotent cell assets.
Pluripotent stem cells are capable of becoming any type of cell in the body, such as muscle, heart, skin or bone, a process called differentiation.
The teratoma assay requires animal testing and a time span of six to eight weeks before scientists can prove that they have a
pluripotent stem cell line.
Researchers from CECAD, the Cluster of Excellence on Aging Research based at the University of Cologne (Koln), defined the mechanisms underlying increased protein quality control of
pluripotent stem cells in a study in round worms.
Human
pluripotent stem cells for use in regenerative medicine or biomedical research come from two sources: embryonic stem cells, derived from fertilized egg cells discarded from IVF procedures; and induced
pluripotent stem cells, where skin cells are reprogrammed to a
pluripotent form.
These induced
pluripotent stem (iPS) cells can develop into most other cell types and are a source of great hope for use in regenerative medicine and the development of new drugs to prevent and treat various illnesses.
Much of the ethical controversy over stem cells derives from the fact that, until now, the only way to obtain human
pluripotent stem cell lines has been to derive them from living human embryos by a process that necessarily destroys embryos," Leon Kass, PhD, the chair of the council, said in releasing the report.
com/research/63186a/induced_pluripoten) has announced the addition of Future Medicine Ltd's new report "Induced
Pluripotent Stem Cells" to their offering.
Citation: Heemin Kang et al, "Small moleculedriven direct conversion of human
pluripotent stem cells into functional osteoblasts," Science Advances, August 2016 DOI: 10.
February 24, 2016 -- Transplantation of retinal pigment epithelial (RPE) cells derived from induced
pluripotent stem cells (iPSCs) is one therapeutic approach that researchers have explored to treat retinal diseases such as macular degeneration.
London, Dec 13 (ANI): For the first time ever, Cincinnati researchers have created functioning human intestinal tissue in the laboratory from
pluripotent stem cells.
