ploidy analysisA flow cytometry technique which evaluates a cell’s chromosome content—a parameter of aggressiveness in cancer. In general, diploidy (i.e., the presence of 2 haploid sets of chromosomes) is a normal or near-normal state; in contrast, anaplastic and aggressive tumours are more often aneuploid or hyperdiploid. Ploidy analysis is used to prognosticate malignancies in bone (osteosarcoma), as well as in bladder, breast, colon, endometrial and ovarian carcinomas, and lymphoma.
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ploidy analysisLab medicine A flow cytometry technique that evaluates a cell's chromosome content–a parameter of aggressiveness in CA; in general, diploidy–ie, the presence of 2 haploid sets of chromosomes, is a normal or near-normal state; in contrast, anaplastic and aggressive tumors are more often aneuploid or hyperdiploid; PA is used to prognosticate CA of bone–osteosarcoma, bladder, breast, colon, endometrium, lymphoma, ovary. See Flow cytometry, S-phase analysis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.