ploidy analysis

ploidy analysis

A flow cytometry technique which evaluates a cell’s chromosome content—a parameter of aggressiveness in cancer. In general, diploidy (i.e., the presence of 2 haploid sets of chromosomes) is a normal or near-normal state; in contrast, anaplastic and aggressive tumours are more often aneuploid or hyperdiploid. Ploidy analysis is used to prognosticate malignancies in bone (osteosarcoma), as well as in bladder, breast, colon, endometrial and ovarian carcinomas, and lymphoma.

ploidy analysis

Lab medicine A flow cytometry technique that evaluates a cell's chromosome content–a parameter of aggressiveness in CA; in general, diploidy–ie, the presence of 2 haploid sets of chromosomes, is a normal or near-normal state; in contrast, anaplastic and aggressive tumors are more often aneuploid or hyperdiploid; PA is used to prognosticate CA of bone–osteosarcoma, bladder, breast, colon, endometrium, lymphoma, ovary. See Flow cytometry, S-phase analysis.
References in periodicals archive ?
Ploidy analysis performed on seed at the time of deployment confirmed that 3N DEBY and 3N hANA were 100% triploid.
Other ancillary techniques, including conventional cytogenetics (karyotype), DNA ploidy analysis (flow cytometry, image analysis), and fluorescence in situ hybridization, have the limitation of not being able to establish maternal/parental contributions of chromosome complements and cannot absolutely determine the true diagnosis.
Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases.
The published incidence of histopathologically and ploidy analysis verified partial hydatidiform mole is about 1 in 700 first- and second-trimester abortions [21], and rates in East Africa are not known.
Finci, "Oncocytic muco-epidermoid carcinoma of the parotid gland: report of a case with DNA ploidy analysis and review of the literature," Pathology International, vol.
Vicioso-Recio, "Sarcomatoid transitional cell carcinoma of the renal pelvis: a report of five cases with clinical, pathological, immunohistochemical and DNA ploidy analysis," Pathology--Research and Practice, vol.
(a) MK-PROs DNA ploidy analysis (4N and [greater than or equal to]8N) after different small molecules treatment.
"Cellular angiofibroma of the vulva with DNIA ploidy analysis," Int J Gynecol Pathol.
disorders CD4, CD8 count Antiglobin test, Platelet function disorder, ploidy analysis
Combination of immunohistochemistry and ploidy analysis to assist histopathological diagnosis of molar diseases.
Nuclear DNA, chloroplast DNA, and ploidy analysis clarified biological complexity of the Vandenboschia radicans complex (Hymenophyllaceae) in Japan and adjacent areas.