pleonosteosis

pleonosteosis

 [ple″on-os″te-o´sis]
abnormally increased ossification.
Léri's pleonosteosis a hereditary syndrome of premature and excessive ossification, with short stature, limitation of movement, broadening and deformity of digits, and a face similar to that seen with down syndrome.

ple·on·os·te·o·sis

(plē'on-os'tē-ō'sis),
Superabundance of bone formation.
[pleo- + G. osteon, bone, + -osis, condition]

ple·on·os·te·o·sis

(plē'on-os-tē-ō'sis)
Superabundance of bone formation.
[pleo- + G. osteon, bone, + -osis, condition]
References in periodicals archive ?
The muscular-skeletal features merely configure Leri's pleonosteosis (LP) phenotype, a very rare disorder first described in 1921 [1].
Leri's pleonosteosis was originally described as a rare congenital rheumatic disease frequently overlapping with other muscoloskeletal diseases [1].
The present work describes an 8-year-old girl that showed a Leri's pleonosteosis phenotype associated with neurodevelopmental disorders and psychiatric symptoms.
Thus, our 8-year-old girl presented with clinical and genetic features of Leri's pleonosteosis, within a larger microduplication involving different genes not strictly related to our patient phenotype.
This case report describes an 8-year-old girl with micro-duplication of chromosome 8q22.1 characterized by Leri's pleonosteosis features, neurodevelopmental, and psychiatric disorders.
The report provides a description of a possible wider phenotype of Leri's pleonosteosis disease, encompassing not only the physical signs but also psychiatric symptoms, and supports the conception of a more integrated mentalphysical health care approach.
Carim et al., "Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis," Annals of the Rheumatic Diseases, vol.
Shaw, "Leeri's pleonosteosis," British Journal of Radiology, vol.
Watson-Jones, "Leeri's pleonosteosis, carpal tunnel compression of the media nerves and Morton's metatarsalgia," Journal of Bone and Joint Surgery, vol.
Yeoman, "Leri's pleonosteosis," Proceedings of the Royal Society of Medicine, vol.
Block, "Leri's pleonosteosis; a study of a family with a review of the literature," Journal of Bone and Joint Surgery, vol.