atypical lipoma

(redirected from pleomorphic lipoma)

a·typ·i·cal li·po·ma

lipoma, occurring primarily in older men on the posterior neck, shoulders, and back, which is benign but microscopically atypical, containing giant cells with multiple overlapping nuclei forming a circle.
Synonym(s): pleomorphic lipoma

atypical lipomatous tumour

A well-circumscribed, low-grade malignancy which arises in deep soft tissue of extremities, retroperitoneum, and groin, for which the term “well-differentiated liposarcoma” is increasingly preferred. As a general rule, the deeper the tumour, the more likely it is to recur.
Management Complete excision is curative.

a·typ·i·cal li·po·ma

(ā-tip'i-kăl li-pō'mă)
Lesion, occurring primarily in older men on the posterior neck, shoulders, and back, which is benign but microscopically atypical, containing giant cells with multiple overlapping nuclei forming a circle.
Synonym(s): pleomorphic lipoma.

a·typ·i·cal li·po·ma

(ā-tip'i-kăl li-pō'mă)
Lesion, occurring primarily in older men on the posterior neck, shoulders, and back, which is benign but microscopically atypical, containing giant cells with multiple overlapping nuclei forming a circle.
Synonym(s): pleomorphic lipoma.
References in periodicals archive ?
Primary variants of lipoma can be listed as angiolipoma, myolipoma, fibrolipoma, angiomyolipoma, myelolipoma, chondroid lipoma, chondrolipoma, fusiform cell, and pleomorphic lipoma. Chondrolipomas are characterized by presence of mature cartilage and proliferation of mature adipocytes.
According to microscopic characteristics, lipomas are classified as classic lipoma, fibrolipoma, angiolipoma, spindle cell lipoma, pleomorphic lipoma, myxoid lipoma, sialolipoma, and intramuscular lipoma.
Intradermal spindle cell/ pleomorphic lipoma: a distinct subset.
Lipoma variants are also described, such as fibrolipoma, osteolipoma, chondroid lipoma, intramuscular lipoma, pleomorphic lipoma, and lipoblastoma.
According to World Health Organization, lipomas are categorized into 9 entities, one of which is spindle cell/ pleomorphic lipoma [2].
In conclusion, giant liposarcomas in scapular region are extremely rare; and possible differential diagnosis may be lipoma, lipoblastoma, pleomorphic lipoma, chondroid lipoma, hibernoma and neurofibroma etc.
Histologically, they can be classified as simple lipoma, fibrolipoma, spindle cell lipoma, intramuscular or infiltrating lipoma, angiolipoma, pleomorphic lipoma, myxoid lipoma, and atypical lipoma.
Subconjunctival herniated orbital fat: a benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor.
Several variants described include angio-lipoma, chondroid lipoma, myo-lipoma, spindle cell lipoma, pleomorphic lipoma, fibrolipoma, osteolipoma/chondrolipoma, mylelipoma, adenolipoma, perineural lipoma, myxoid lipoma.
Histologically, spindle-cell lipoma is a distinctive type of lipoma on a continuum with pleomorphic lipoma. It accounts for approximately 1.5% of all adipose tissue neoplasms.
For the 75 cases considered nonamplified, diagnoses were lipoma (n = 46); intramuscular lipoma (n = 11); pleomorphic lipoma (n = 1); myofibroblastoma (n = 1); sclerosing mesenteritis (n = 2); lipoma with fat necrosis (n = 4); pleomorphic sarcoma, not otherwise specified (n = 2); low-grade spindle cell neoplasm not further classifiable (n = 1); and benign mesenchymal myxoid neoplasm not further classifiable (n = 1).
(1) According to histopathological findings, they are sub classified into conventional lipoma, fibrolipoma, angiolipoma, fusiform cell lipoma, myolipoma and pleomorphic lipoma. (1) Retroperitoneal lipomas are extremely rare, slowly growing benign tumours of adipose tissue.