pleiotropic


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Related to pleiotropic: Pleiotropic Genes

plei·o·trop·ic

(plī'ō-trop'ik),
Denoting, or characterized by, pleiotropy.
Synonym(s): polyphenic

plei·o·trop·ic

(plī-ō-trō'pik)
Denoting, or characterized by, pleiotropy.
References in periodicals archive ?
The KIT-ligand (steel factor) and its receptor c-KIT/W: pleiotropic roles in gametogenesis and melanogenesis.
IL-21 has pleiotropic actions in controlling a complex range of immune components through IL-21R; loss of function of IL-21R can induce immunodeficiency syndrome.
Pleiotropic effects refer to actions other than those for which the agent was specifically developed.
Pleiotropic effects of statins and related pharmacological experimental approaches.
Cholesterol-lowering statins have numerous pleiotropic ef-fects--that is, benefits other than the one for which the drug is intended.
The potentially pleiotropic effects of vitamin D analogues support the hypothesis that vitamin D deficiency is a universal risk factor.
Interleukin-6 (IL-6) family cytokines are pleiotropic secreted factors that have been shown to play an important role in cancer metastasis, yet little is known about their role in the metastatic process of prostate cancer.
Psychiatrists should start conceptualizing DSM-5 disorders not as freestanding medical conditions but as syndromes--collections of inter-related clinical phenotypes resulting from pleiotropic genes.
Other explanations offered include the suppression of coenzyme Q10 production, as well as the pleiotropic effects of statins.
This significantly increases the power to discover new genes by leveraging the combined power across multiple GWAS of pleiotropic traits and diseases," said Dale.
Modern scientific research demonstrated that curcumin is a highly pleiotropic molecule that interacts with numerous molecular targets.