pleiotropic


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Related to pleiotropic: Pleiotropic Genes

plei·o·trop·ic

(plī'ō-trop'ik),
Denoting, or characterized by, pleiotropy.
Synonym(s): polyphenic

plei·o·trop·ic

(plī-ō-trō'pik)
Denoting, or characterized by, pleiotropy.
References in periodicals archive ?
Curcumin is shown to be a highly pleiotropic molecule that interacts with numerous molecular targets directly by binding and modulating their activity, or indirectly by regulating their functions (Zhou et al.
Our study provokes further discussion on the pleiotropic benefits of statin drugs.
000), pleiotropic, multiple congenital anomaly syndrome characterized by the primary clinical triad of polysyndactyly, macrocephaly, and hypertelorism (5).
The pleiotropic effects of Kaposi's sarcoma herpesvirus.
Although the majority of effects could be ascribed to a beneficial effect on the lipid profile, the statins exert beneficial effect, called pleiotropic effect, beyond those predicted by their cholesterol-lowering actions.
TNF is a pleiotropic cytokine central to the development and homeostasis of the immune system; a regulator of cell activation, differentiation, and death; and is implicated in a number of biological processes such as acute and chronic inflammation, autoimmunity, infection, and tumor responses.
Many of the agents for TBI that are currently being studied in early-phase clinical trials are pleiotropic and include erythropoietin, cyclosporine, allopregnanolone, statins, and growth hormone.
9:40 am PLEIOTROPIC ROLE OF METALLOTHIONEIN-3 (MT-3)
7) The findings presented in a previous report revealed a molecular interaction among Gal-3 with [beta]-catenin/TCF complex, and the similarities in the pleiotropic functions of both [beta]-catenin and Gal-3 in the Wnt signaling pathway.
While numerous studies have concluded that diets rich in fruits and vegetables support the body in fighting neurological decline through antioxidant mechanisms associated with their high flavonoid content, the importance of tea's polyphenolic flavonoids in supporting healthy brain cells appears to go beyond the simple oxygen species scavenging, involving pleiotropic effects on numerous biological pathways to help keep human brain cells from dying and even help repair them when they are subjected to insults that damage the cells' DNA.
ask "Is symbiosis evolution influenced by the pleiotropic role of programmed cell death in immunity and development?