platelet-aggregating factor


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plate·let-ag·gre·gat·ing fac·tor (PAF),

phospholipid mediator of platelet aggregation, inflammation, and anaphylaxis. Produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of PAF have been identified that vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction.

plate·let-ag·gre·gat·ing fact·or

(PAF) (plāt'lĕt ag'grē-gā'ting fak'tŏr)
Phospholipid mediator of platelet aggregation, inflammation, and anaphylaxis; produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells. Several molecular species of PAF have been identified that vary in the length of the O-alkyl side chain. It is an important mediator of bronchoconstriction.
Synonym(s): platelet-activating factor.
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