Platelet glycoprotein receptor | definition of platelet glycoprotein receptor by Medical dictionary
platelet glycoprotein receptor
platelet glycoprotein receptor One of a range of receptors on blood platelets that bind glycoproteins. Platelet glycoprotein receptor IIb/IIIa binds fibrinogen, thereby promoting platelet aggregation and the formation of a blood clot within a blood vessel. This receptor can be blocked by various substances such as HIRUDIN or a number of synthetic drugs such as tirofiban.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive
Flow cytometric assay of platelet glycoprotein receptor
numbers in hyperlipidemia.
A polymorphism of a platelet glycoprotein receptor
as an inherited risk factor for coronary thrombosis.
They adhere to the lysine-binding sites of plasminogen and plasmin to interfere with plasmins ability to digest fibrinogen, fibrin, and platelet glycoprotein receptors