platelet concentrate

platelet concentrate

A blood product prepared from a single donor, which transiently increases platelet count by 5-10 x 109/L/m2 body surface area (5–10,000/µL) if thrombocytopaenia (decreased platelet count) is not due to increased platelet destruction.

Thresholds
Bleeding due to thrombocytopaenia is unlikely if the platelets are > 50,000/µL, and highly likely at a platelet count of < 5,000/µL. The grey zone between these two depends on local practice, with most platelet concentrates being administered at < 10,000/µL.

Adverse reactions
Febrile transfusion reactions are related to bioreactive substances (IL-1β and IL-6) in supernatant, which increases with increased storage and increased number of leukocytes in stored unit.

platelet concentrate

Transfusion medicine A product prepared from a single donor, which transiently ↑ platelet count by 5-10 x 109/L/M2 body surface area, if thrombocytopenia is not due to ↑ destruction Adverse reactions Febrile transfusion reactions are related to bioreactive substances–IL-1β and IL-6 in supernatant, which ↑ with ↑ storage and ↑ number of WBCs in stored unit. See Platelet transfusion.

platelet concentrate

Platelets prepared from a single unit of whole blood or plasma and suspended in a specific volume of the original plasma. This blood fraction must be used before the expiration date shown on its label. Platelets are stored at room temperature (22°C) either in plasma or in a concentrated form as platelet-rich plasma.
References in periodicals archive ?
Electronic auction: supply of a system for the preparation of platelet concentrate by the lts bullet method
PRF dwells among a new generation of platelet concentrate that jump-starts the healing process to maximize predictability.
Majority of patients requiring platelet concentrate transfusion were suffering from viral haemorrhagic fever.
2010) Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial platelet-rich plasma versus corticosteroid injection with a 1year follow-up.
Platelet-rich fibrin (PRF) is a new-generation platelet concentrate with a simplified technique.
Transfusion of the platelet concentrate is done when needed.
It should be noted for planning purposes that the platelet units in "1:1:1" refer to platelet concentrate volumes from whole-blood derived platelets (imagine literally reconstituting a unit of whole blood that has been separated by centrifugation into red cells, plasma and platelets--with anticoagulant and red cell additive solution added, thus diluting final product concentrations by about a third).
Platelet rich plasma (PRP) is an autologus platelet concentrate obtained by processing whole blood and containing red and white blood cells, plasma and platelets (Dahlgren, 2009).
Background: This study investigated the effects of Riboflavin (RB) combined with different doses of UV on Platelet Concentrate (PC) which was infected by three models of virus.
Platelet counts trended downward with processing from whole blood (WB) to platelet concentrate (PC), although these changes were not significant (P =.
The method reports that by adding a stressor to the platelet concentrate the differential impedance of the stressed sample versus an unstressed sample is an indication of the presence of bacteria.
The data reveals that packed cells occupy the first place with FFP being a close second, with platelet concentrate, PRP and cryoprecipitate lagging far behind.

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