platelet concentrateA blood product prepared from a single donor, which transiently increases platelet count by 5-10 x 109/L/m2 body surface area (5–10,000/µL) if thrombocytopaenia (decreased platelet count) is not due to increased platelet destruction.
Bleeding due to thrombocytopaenia is unlikely if the platelets are > 50,000/µL, and highly likely at a platelet count of < 5,000/µL. The grey zone between these two depends on local practice, with most platelet concentrates being administered at < 10,000/µL.
Febrile transfusion reactions are related to bioreactive substances (IL-1β and IL-6) in supernatant, which increases with increased storage and increased number of leukocytes in stored unit.
platelet concentrateTransfusion medicine A product prepared from a single donor, which transiently ↑ platelet count by 5-10 x 109/L/M2 body surface area, if thrombocytopenia is not due to ↑ destruction Adverse reactions Febrile transfusion reactions are related to bioreactive substances–IL-1β and IL-6 in supernatant, which ↑ with ↑ storage and ↑ number of WBCs in stored unit. See Platelet transfusion.
Platelets prepared from a single unit of whole blood or plasma and suspended in a specific volume of the original plasma. This blood fraction must be used before the expiration date shown on its label. Platelets are stored at room temperature (22°C) either in plasma or in a concentrated form as platelet-rich plasma.