platelet antigen

platelet antigen

Transfusion medicine An antigen on the surface of platelets that may evoke production of antibodies, causing neonatal alloimmune thrombocytopenia and post-transfusion purpura, most commonly as a reaction to the P1A1 antigen in P1A1 antigen-negative recipients; other PAs causing purpura include PlA2, HLA-A2 and Baka
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When previously exposed females receive blood/ Platelet transfusion, it triggered a B cell-mediated immune response with increase in antibodies against human platelet antigen, which destroy normal platelets.
Determination of human platelet antigen typing by molecular methods: Importance in diagnosis and early treatment of neonatal alloimmune thrombocytopenia.
No antibodies to the human platelet antigen (HPA) system detected by this screen.
Idiopathic thrombocytopenia is due to an autoimmune process caused by auto antibodies binding to the platelet antigen resulting in the destruction of platelets.
Antibodies developed against fetal thrombocytes due to fetal-maternal platelet antigen incompatibility cause thrombocytopenia both in intrauterine period and afterwards.
Both biological factors--such as human platelet antigen dysfunction, impaired vascular function, reduced heart rate variability--and behavioral and/or social mechanisms--such as diet, exercise, medication adherence, tobacco use, social isolation, and chronic life stress have been suggested as possible links between depression and heart disease.
Both biological factors--such as human platelet antigen dysfunction, impaired vascular function, and reduced heart rate variability--and behavioral and/or social mechanisms--such as diet, exercise, medication adherence, tobacco use, social isolation; and chronic life stress--have been suggested as possible links between depression and heart disease.
They discussed a human antibody against the human platelet antigen 5b, and covered a number of topics specific to blood products and related substances.
Rapid genotyping of human platelet antigen 1 (HPA-1) with fluorophore-labelled hybridization probes on the LightCycler.
Then they searched for a particular version of the platelet antigen gene, which codes for a protein known to play a key role in the blood-clotting process.
This disorder, in which the mother makes IgG antibodies to an incompatible platelet antigen that the fetus has inherited from the father, "is the platelet equivalent of Rh disease," said Dr.

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