Fluorescence intensiveness equaled 249 [+ or -] 51 for granulocytes and 212 [+ or -] 51 for
plasmocytes.
(3): intense inflammatory infiltrate (presence of lymphocytes,
plasmocytes, macrophages and neutrophils).
Lymphocytes, monocytes and
plasmocytes composed the interstitial infiltrate.
Bone marrow infiltration was defined as an abnormal percentage of
plasmocytes on bone marrow biopsy (>3.5%
plasmocytes).
Le resultat anatomopathologique pointait en faveur d'une reaction inflammatoire non specifique faisant intervenir des cellules lymphocytes,
plasmocytes et polynucleaires.
Histologic analysis of the skin biopsy specimen showed perivascular lymphocytic infiltrates with admixture of
plasmocytes, consistent with EM (Figure 2).
Histopathological examination of the incisional biopsy specimen showed normal epidermis with superficial focal parakeratosis, and noncaseating tuberculoid granulomas consisting of epithelioid histiocytes,
plasmocytes, and Langhans giant cells in the papillary dermis (Figure 2A and Figure 2B).
These finger-like projections are convolute and surround packages of fibres, as well as a kind of cells as
plasmocytes, lymphocytes and developing red cells.
PDC-E2 is endocytosed by APC and this endocytosis leads to APC maturation and IL-12 secretion which provides the cytokine milieu which is essential for the maintenance of the continuum of proinflammatory T-helper type 1 (Th1) induction arising from naive CD4+ T through antigen presentation; such antigenspecific CD4 T cells help
plasmocytes to produce high-titre AMA targeting PDC-E2.
La proliferation cellulaire etait melee a un infiltrat inflammatoire abondant plus accentue en peripherie et riche en lymphocytes,
plasmocytes et polynucleaires eosinophiles.
It is also observed infiltrated macrophages with myelinic residues phagocytized, lymphocytes and
plasmocytes. In some regions, the blood irrigation is damaged blocking the circulating monocytes arrival, therefore the necrotic tissue is not phagocytized or eliminated, remaining in the region and, possibly, suffering calcification.