plasmin

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Related to plasmin inhibitors: Plasminogen activator inhibitor

plasmin

 [plaz´min]
the active principle of the fibrinolytic or clot-lysing system, a proteolytic enzyme with a high specificity for fibrin and the particular ability to dissolve formed fibrin clots.

plas·min

(plaz'min),
A serine proteinase catalyzing the hydrolysis of peptides and of esters of l-arginine and l-lysine and converting fibrin to soluble products; occurs in plasma as the precursor plasminogen (profibrinolysin) and is activated to plasmin by organic solvents, which remove an inhibitor, and by streptokinase, trypsin, and plasminogen activator, all cleaving a single arginyl-valyl bond; plasmin is responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin

plasmin

/plas·min/ (plaz´min) an endopeptidase occurring in plasma as plasminogen, which is activated via cleavage by plasminogen activators; it solubilizes fibrin clots, degrades other coagulation-related proteins, and can be activated for use in therapeutic thrombolysis.

plasmin

(plăz′mĭn)
n.
A proteolytic enzyme that is formed from plasminogen in blood plasma and dissolves the fibrin in blood clots. Also called fibrinolysin.

plasmin

plasmin

A proteolytic enzyme formed from plasminogen that lyses blood clots; plasmin exists in free and bound–fibrin-adsorbed forms; the former is destroyed as it is formed by antiplasmins, the latter acts as a serine endopeptidase to solubilize fibrin clots; it hydrolyzes lysine and arginine bonds in certain proteins–eg, fibrinogen, coagulation factors V and VII. See tPA.

plas·min

(plaz'min)
An enzyme hydrolyzing peptides and esters of l-arginine and l-lysine, and converting fibrin to soluble products; responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin.

plasmin

A protein-splitting enzyme in the blood that dissolves FIBRIN clots.

plas·min

(plaz'min)
An enzyme responsible for the dissolution of blood clots.
Synonym(s): fibrinase (2) , fibrinolysin.

plasmin

the active principle of the fibrinolytic or clot-lysing system, a proteolytic enzyme formed from plasminogen which hydrolyzes fibrin, fibrinogen, factor V and other proteins. It has the particular ability to dissolve formed fibrin clots. Called also fibrinolysin.

plasmin inhibitors
include α2-macroglobulin, α1-antitrypsin, C1-inactivator, antithrombin III.