plasmalogen


Also found in: Encyclopedia, Wikipedia.

plasmalogen

/plas·ma·lo·gen/ (plaz-mal´ŏ-jen) any of various phospholipids in which the group at one C1 of glycerol is an ether-linked alcohol in place of an ester-linked fatty acid, found in myelin sheaths of nerve fibers, cell membranes of muscle, and platelets.

plasmalogen

one of a group of phospholipids found in platelets, cell membranes of muscle and myelin sheaths of nerve fibers. In platelets their hydrolysis produces aldehydes which appear to play a significant part in the coagulation function of those cells.
References in periodicals archive ?
Low-concentration ozone reacts with plasmalogen glycerophosphoethanolamine lipids in lung surfactant.
Peroxisomal disease cell lines with cellular plasmalogen deficiency have impaired muscarinic cholinergic signal transduction activity and amyloid precursor protein secretion.
Analyses of the fatty acid pattern of membrane phospholipids and plasmalogen of human spermatozoa have demonstrated significant levels of polyunsaturated acids.
Relative high percentages of the plasmalogen derivatives 16:0DMA and 18:0DMA were also detected.
It mostly exists in the forms of phospholipids phosphatidylcholine (lecithin), lysophosphatidylcholine, choline plasmalogens and sphingomyelin, and is widely distributed in all plant and animal cells (Zeisel, 1990).
In the chromatograms obtained from base-catalyzed methylations, FFA peaks could be identified clearly in addition to FAME, whereas in the chromatogram obtained from the acid-catalyzed methylations, peaks related to acetals (originating from methanolization of the plasmalogens contained in the samples) were identified, as confirmed by GC-MS analysis.
Their origin and how they transform, cholesterol, phospholipids, plasmalogens, polyunsaturated fatty acids, sugars, and proteins into deleterious products.