A bone marrow biopsy and aspirate showed a reactive marrow with eosinophilia and no plasmacytosis
or immunophenotypical evidence of a clonal B lymphocyte population.
(16) In addition, autoimmune hepatitis typically has a more striking plasmacytosis
as well as more significant lobular activity and hepatocellular damage, including bridging necrosis.
Interfollicular areas showed paracortical plasmacytosis
(figure 2, B).
MGUS still requires the presence of a serum monoclonal protein in a concentration of 3 g/dL or less, less than 10% plasmacytosis
in the bone marrow, asymptomatic status, and absence of end-organ damage as traditionally defined in the acronym CRAB (calcium elevation, renal insufficiency, anemia, or bony disease).
was seen in 4 cases (1.8%) and one case of multiple myeloma was reported.
Chen, "Perifollicular granulomas with IgG4 plasmacytosis
: A case report and review of literature," World Journal of Clinical Cases, vol.
Since CKD is predominantly a disease of the elderly so it is not rare to find the co-morbidities including plasmacytosis
, malignancies and their effects on the BM in patients of CKD.
[12-15] Many of these studies highlight the difficulties in diagnosis of MM in HIV-positive patients, as the two diseases share some common clinical features, especially anaemia, fatigue, weight loss, bone marrow plasmacytosis
, renal insufficiency and recurrent bacterial infections.
Histopathological examination of the skin was consistent with neutrophilic urticaria (Figure 2a) and lymph nodes showed follicular hyperplasia and polytypic plasmacytosis
(Figure 2b) with polyclonality to IgH/K/L genes.
 cervical, and right perirenal lymphadenopathies HHV8+, EBV+ HCV+, HIV- M/61 Submandibular, Preserved inguinal, architecture and paratracheal germinal centers M/61 lymphadenopathies were replaced HHV8+, EBV+, HIV- partially or completely by tumor cells: plasmablasts and anaplastic cells Normal mantle zones Prominent plasmacytosis
in the interfollicular zones F/63 Left leg swelling and paraesthesia para-aortic lymphadenopathy Not available Taris et F/49 Isolated jugular Nodular al.
Stromal reactions of chronic inflammation and immune reaction in bone marrow include chronic granulomatous inflammation, reactive changes, plasmacytosis
, histiocytic hyperplasia, chronic inflammation with fibrosis and amyloidosis.8
The megakaryoblasts were markedly reduced with reactive plasmacytosis
. CD117 and CD34 each marked approximately 50% of the myeloid progenitor cells.