plasmacytoma

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Related to plasmacytomas: soft tissue plasmacytoma

plasmacytoma

 [plaz″mah-si-to´mah]
1. a plasma cell dyscrasia.
2. a discrete, presumably solitary, plasma cell tumor mass.

plas·ma·cy·to·ma

(plaz'mă-sī-tō'mă),
A discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of various extramedullary sites; in humans, such lesions are probably the initial phase of developing plasma cell myeloma.
[plasmacyte + G. -oma, tumor]

plasmacytoma

/plas·ma·cy·to·ma/ (plaz″mah-si-to´mah)

plasmacytoma

[plaz′məsītō′mə] pl. plasmacytomas, plasmacytomata,
a focal neoplasm containing plasma cells that may develop in the bone marrow, as in multiple myeloma, or outside the bone marrow, as in tumors of the viscera and the mucosa of the nasal, oral, and pharyngeal areas. Also called peripheral plasma cell myeloma, plasma cell tumor.

plasmacytoma

Hematology A tumor composed of malignant plasma cells. See Plasma cell.

plas·ma·cy·to·ma

(plaz'mă-sī-tō'mă)
A discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of various extramedullary sites; in humans, such lesions are probably the initial phase of developing plasma cell myeloma.
[plasmacyte + G. -oma, tumor]

plas·ma·cy·to·ma

(plaz'mă-sī-tō'mă)
A discrete, presumably solitary mass of neoplastic plasma cells in bone or in one of various extramedullary sites; in humans, such lesions are probably the initial phase of developing plasma cell myeloma.
[plasmacyte + G. -oma, tumor]

plasmacytoma (plaz´məsītō´mə),

n the primary soft tissue plasma cell tumors of the oral, pharyngeal, and nasal mucous membranes. The lesion consists of typical and atypical plasma cells, and its behavior is unpredictable. See also myeloma, solitary plasma cell and dyscrasia.
plasmacytoma, soft tissue,
n a primary plasma cell tumor of the nasal, pharyngeal, and oral mucosa that has no apparent primary bone involvement. The lesions are sessile or polypoid sessile masses in the mucous membrane. The majority remain localized, but metastases have been reported.

plasmacytoma

any focal neoplasm of plasmacytes, including those of multiple myeloma (immunoblastic sarcoma). Isolated plasmacytomas may occur outside the bone marrow (extramedullary plasmacytomas), affecting such tissues as the nasal, oral, pharyngeal and gastrointestinal mucosa and other viscera; called also plasma cell tumor.
References in periodicals archive ?
Nonsecretory multiple myeloma in a 26-year-old man with acquired immunodeficiency syndrome, presenting with multiple extramedullary plasmacytomas and osteolytic bone disease.
A recent report suggested that IgA-expressing nodal and extranodal plasmacytoma may represent a distinct form of extramedullary plasmacytoma characterized by young age, frequent nodal involvement, and low risk of progression to PCM.
Fine needle aspiration cytology in extramedullary plasmacytoma.
A case of extramedullary plasmacytoma arising from the lacrimal gland: a case report.
Whereas, Kim et al found that the prognostic factors for reduced overall survival rate in patients with IgD multiple myeloma were advanced age, the presence of cytogenetic abnormalities such as del(13) or hypodiploidy, extramedullary plasmacytoma, and high serum p2 microglobulin.
Anghel and colleagues performed a literature review of testicular plasmacytoma cases and previous or concurrent multiple myeloma or EMP to assess survival.
It has been observed that all base of the skull infiltrating plasmacytomas were associated with multiple myeloma.
Plasmacytoma is a rare plasma cell tumour that arises from plasma cells and accounts for about 3-5% of all plasma cell malignancies.
The cause of the neuropathy in many cases of myeloma is not clear, but neurotoxic drugs, amyloidosis, and spinal cord or nerve root compression by plasmacytoma or lytic or extramedullary bone disease are the most common causes (6).
Overall, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically.