plasma exchange

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Related to plasma exchange: plasma exchange therapy


1. the substitution of one thing for another.
2. to substitute one thing for another.
gas exchange the passage of oxygen and carbon dioxide in opposite directions across the alveolocapillary membrane.
health care information exchange in the nursing interventions classification, a nursing intervention defined as providing patient care information to health professionals in other agencies.
impaired gas exchange a nursing diagnosis approved by the North American Nursing Diagnosis Association, defined as excess or deficit in oxygenation and/or carbon dioxide elimination at the alveolocapillary membrane (see gas exchange). Etiological and contributing factors include an altered oxygen supply, changes in the alveolar-capillary membrane, altered blood flow, and altered oxygen-carrying capacity of the blood. Defining characteristics include changes in mental status such as confusion, somnolence, restlessness, and irritability; ineffective coughing and inability to move secretions from the air passages; hypercapnia; and hypoxia. For specific medical treatments and nursing interventions, see airway clearance, ineffective; breathing patterns, ineffective; chronic airflow limitation; and anemia.
plasma exchange see plasma exchange.


1. the fluid portion of the lymph.
2. the fluid portion of the blood, in which the formed elements (blood cells) are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting. Called also blood plasma. adj., adj plasmat´ic, plas´mic.

Of the total volume of blood, 55 per cent is made up of plasma. It is a clear, straw-colored liquid, 92 per cent water, in which are contained plasma proteins, inorganic salts, nutrients, gases, waste materials from the cells, and various hormones, secretions, and enzymes. These substances are transported to or from the tissues of the body by the plasma.

Plasma obtained from blood donors is given to persons suffering from loss of blood or from shock to help maintain adequate blood pressure. Since plasma can be dried and stored in bottles, it can be transported almost anywhere, ready for immediate use after addition of the appropriate fluid. Plasma can be given to anyone, regardless of blood type. (See also transfusion.)

Plasma volume is sometimes measured in order to calculate the total blood volume. The most common method for determining plasma volume is by injection of a dye (T-1824, called Evans blue) into the circulating blood and, after the dye has been dispersed throughout the body, using the dilution of the dye to calculate the total blood volume.
antihemophilic human plasma normal human plasma that has been processed promptly to preserve the antihemophilic properties of the original blood; used for temporary correction of bleeding tendency in hemophilia.
blood plasma plasma (def. 2).
citrated plasma blood plasma treated with sodium citrate, which prevents clotting.
plasma exchange the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
fresh frozen plasma plasma separated from whole blood and frozen within 8 hours; it contains all the coagulation factors.
plasma thromboplastin antecedent deficiency hemophilia C.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Schmitz, "A randomized trial comparing intravenous immune globulin and plasma exchange in Guillain-Barre syndrome.
Caption: Figure 5: The expression of serum miR-200c and miR-371-5p in KD patients undergoing the therapy; IVIG: IVIG therapy; ADT: additional drug treatments; PE: plasma exchange; Good-IVIG: KD patients with a good response to IVIG therapy; No-IVIG: KD patients with no response to IVIG therapy; No-IVIG and NNPE: KD patients with no response to IVIG therapy and not needing plasma exchange; NPE: KD patients needing plasma exchange; ** P value < 0.01, paired t-test.
The treatment of anti-GBM disease focuses on a combination of plasma exchange, cyclophosphamide, and prednisone.
Concurrent plasma exchange impedes the response to eculizumab and should be avoided unless there is a compelling reason for continuation.
In contrast to plasma exchange and IVIg, corticosteroids are mainly ineffective in GBS [81] either alone or in combination with IVIg [82].
Plasma exchange is an extracorporeal procedure and thus requires anticoagulation.
Every 2-3 days, patients underwent sequential plasma exchange or hemodialysis.
Patient responded well to plasma exchange treatment and was able to be discharged home in a stable condition.
Postoperative TTP responds to plasma exchange faster than classical TTP, but also progresses more rapidly and usually fatally if untreated or if treatment is commenced late.
Plasma exchange (PE) or plasmapheresis involves the separation and removal of the blood cells and other substances from the plasma by centrifugation (based on cell density) or ultrafiltration using large-pore hemofilters (based on molecular size) [50].
The patient was admitted to the intensive care unit (ICU) with diffuse alveolar hemorrhage and was started on pulse methylprednisolone, plasma exchange, and cyclophosphamide.