plasma cell


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plas·ma cell

an ovoid cell with an eccentric nucleus; the cytoplasm is strongly basophilic because of the abundant RNA in its endoplasmic reticulum; plasma cells are derived from B lymphocytes and are active in the formation and secretion of antibodies.
Synonym(s): plasmacyte
Farlex Partner Medical Dictionary © Farlex 2012

plasma cell

n.
Any of the antibody-secreting cells found in lymphoid tissue and derived from B cells upon lymphokine stimulation and reaction with a specific antigen. Also called plasmacyte.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

plas·ma cell

(plaz'mă sel)
An ovoid cell with an eccentric nucleus having chromatin arranged like a clock face or spokes of a wheel; the cytoplasm is strongly basophilic because of the abundant RNA in its endoplasmic reticulum; plasma cells are derived from B lymphocytes and are active in the formation of antibodies.
Synonym(s): plasmacyte.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

plasma cell

One of a number of large oval cells, cloned from a selected B LYMPHOCYTE, that synthesize large quantities of the required IMMUNOGLOBULIN (antibody).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Plasma cell

Type of white blood cell that produces antibodies; derived from an antigen-specific B-cell.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

plas·ma cell

(plaz'mă sel)
Ovoid cell with an eccentric nucleus; derived from B lymphocytes and active in formation and secretion of antibodies.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
As to this case, our impression is that there is no relation between the intensity of the thyroiditis, the total number of IgG4-positive plasma cells and the IgG4/IgG ratio.
Langabeer, "The JAK2 V617F mutation in plasma cell neoplasms with co-existing erythrocytosis," Journal of Clinical and Diagnostic Research, vol.
An explanation is that besides IFN-[alpha], there are other cytokines such as IL-6, IL-12, APRIL, and BAFF elicited by pDC that can influence the synthesis of antibody subsets and plasma cell differentiation [75-79].
50% of myeloma cases with plasmablastic morphology in our series showed stage III disease with a plasma cell burden more than 50%.
Genetically, extramedullary plasmacytomas share many features of other plasma cell disorders, such as recurrent losses in chromosome 13, chromosome arm 1p, and chromosome arm 14q, as well as gain in chromosome arms 19p, 9q, and 1q [9].
A bone marrow biopsy revealed 12% plasma cells with an immunoglobulin heavy-chain gene rearrangement.
Since then, several other staging systems have been proposed using other known prognostic factors, including C-reactive protein albumin and plasma cell labeling index [5-8], but the one that gained wide acceptance was the international staging system (ISS) that was published in 2005 [4].
These results suggested that plasma cell infiltration in interstitial lesions has a stronger impact on graft survival than does interstitial infiltration by other cell types.
An increased incidence of plasma cell tumours has been shown in HIV-positive patients, and tend to occur at unusual sites, such as the skin, soft tissues, breasts, testes and oral cavity.
(6) Systemic haematological abnormalities such as hyperglobulinemia and iron refractory anaemia have been documented in some patients with LPM, believed by some to be due to the plasma cell infiltrate.
Dysregulation of plasma cell production and maintenance could lead to autoimmune diseases and multiple myeloma.