the biomarker could be associated with the risk of flow-limiting thrombus formation once a plaque rupture
The designation of AMI is no longer restricted to individuals with acute coronary plaque rupture
causing a decreased oxygen supply (type I).
Circadian variation of plaque rupture
in acute myocardial infarction.
The sudden and unexpected passing of Tim Russert, host of NBC's Meet the Press, is thought to have been the result of a vulnerable plaque rupture
The study hypothesis was that inhibition of joint inflammation using anti-TNF agents might reduce the inflammation that triggers atherosclerotic plaque rupture
and acute coronary and cerebrovascular events, he continued.
is often associated with the breakdown of ECM in the shoulder region of a plaque (4,5).
1) When there is also high circumferential stress at the luminal border of the plaque, plaque rupture
is more likely to occur.
As many as 50 percent of acute coronary syndromes and myocardial infarction may be due to plaque rupture
Inflammation increases the risk of the plaque rupture
in the arteries, but the underlying mechanisms for inflammation are not clear.
And this inflammation is a key factor in plaque rupture
, said Dr.
The definitive reasons for plaque rupture
are unknown, but inflammation appears to play a major role (2).
The novel test that BG Medicine expects to develop aims to use the biomarker discovered by CARIM to identify plaque rupture
in patients early, for instance, when the blockage is temporary or not complete and has not yet caused the common signs and symptoms of heart attack or stroke.