plaque


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plaque

 [plak]
1. any patch or flat area.
2. a superficial, solid, elevated skin lesion with a diameter equal to or greater than 1.0 cm (0.5 cm according to some authorities); see also papule.
atheromatous plaque fibrous plaque.
dental plaque a dense, nonmineralized, highly organized biofilm of microbes, organic and inorganic material derived from the saliva, gingival crevicular fluid, and bacterial byproducts. It plays an important etiologic role in the development of dental caries and periodontal and gingival diseases; calcified plaque forms dental calculus.
fibrous plaque the lesion of atherosclerosis, a white to yellow area within the wall of an artery that causes the intimal surface to bulge into the lumen; it is composed of lipid, cell debris, smooth muscle cells, collagen, and, in older persons, calcium. Called also atheromatous plaque.
Hollenhorst p's atheromatous emboli containing cholesterol crystals in the retinal arterioles.
pleural p's opaque white plaques on the parietal pleura, visible radiographically in cases of asbestosis.
senile p's microscopic lesions composed of fragmented axon terminals and dendrites surrounding a core of amyloid seen in the cerebral cortex in Alzheimer's disease.

plaque

(plak),
1. A patch or small differentiated area on a body surface (for example, skin, mucosa, or arterial endothelium) or on the cut surface of an organ such as the brain; in skin, a circumscribed, elevated, superficial, and solid area exceeding 1 cm in diameter.
2. An area of clearing in a flat confluent growth of bacteria or tissue cells, such as that caused by the lytic action of bacteriophage in an agar plate culture of bacteria, by the cytopathic effect of certain animal viruses in a sheet of cultured tissue cells, or by antibody (hemolysin) produced by lymphocytes cultured in the presence of erythrocytes and to which complement has been added.
3. A sharply defined zone of demyelination characteristic of multiple sclerosis.
4.
[Fr. a plate]

plaque

(plăk)
n.
1. A scaly patch on a body part, especially the skin.
2. A biofilm of bacteria in a matrix of polysaccharides and other substances on the surface of a tooth or teeth.
3.
a. A deposit of fatty material on the inner lining of an arterial wall, characteristic of atherosclerosis.
b. The material that such a deposit is composed of.
4. A deposit consisting mainly of beta-amyloid and degenerating nerve tissue, found in the brain tissue of people with Alzheimer's disease.
5. A sharply defined zone of demyelination in the central nervous system characteristic of multiple sclerosis.
6. A clear, often round patch of lysed cells in an otherwise opaque layer of a bacteria or cell culture.

plaque

Cardiology
An early lesion of atherosclerosis which may be found in persons of any age in large vessels.
 
Dentistry
A soft sticky substance on teeth composed of bacteria and saliva; an indurated soft mass of polysaccharides and bacteria—e.g., Lactobacillus acidophilus, Streptococcus mutans.

Dermatology
A flat, solid, elevated, ≥ 1.0-cm-diameter skin nodule formed either by extension or coalescence of papules of lichen amyloidosis, lichen simplex chronicus, lichen planus, or psoriasis; a “plaque” stage occurs in certain skin tumours (e.g., the second stage of Kaposi sarcoma), and evolving mycosis fungoides.
 
Molecular biology
A clear area on a lawn of bacterial cells caused by the lysis of infected cells by a phage.
 
Neuropathology
Shadow plaques—one of multiple, irregularly shaped and sharply demarcated lesions (focal demyelinisation) in the gray and white matter in the brain of patients with multiple sclerosis.

plaque

Cardiology An early lesion of ASHD found in persons of any age in larger vessels Dentistry A soft sticky substance on teeth composed of bacteria and saliva; an indurated gob of polysaccharides and bacteria–eg, Lactobacillus acidophilus, Streptococcus mutans. See Periodontitis Dermatology A flat, solid, elevated ≥ 1. 0 cm in diameter skin nodule formed either by extension or coalescence of papules of lichen amyloidosis, lichen simplex chronicus, lichen planus, psoriasis; a 'plaque' stage occurs in certain skin tumors–eg, the 2nd stages of KS, mycosis fungoides Neurology 'Shadow plaques' Multiple, irregularly shaped, and sharply demarcated lesions–focal demyelinization in the gray and white matter in the brain of Pts with MS. Asymmetric unit membrane plaque, Atherosclerotic plaque, Complicated plaque, Fibrous plaque, Multiple sclerosis, Parietal pleural plaque, Senile plaque, Shadow plaque, Soldier's plaque

plaque

(plak)
1. A patch or small, differentiated area on a body surface (e.g., skin, mucosa, or arterial endothelium) or on the cut surface of an organ such as the brain.
2. An area of clearing in a flat, confluent growth of bacteria or tissue cells.
3. A sharply defined zone of demyelination characteristic of multiple sclerosis.
[Fr. a plate]

plaque

1. An area of ATHEROMA found in the inner lining of arteries in the disease of ATHEROSCLEROSIS.
2. A sticky mixture of food debris, saliva and bacteria that persists around the necks of uncleaned teeth and is the main cause of tooth decay.

plaque

  1. a clear area in a ‘lawn’ of bacterial growth, in which the bacteria have undergone LYSIS due to BACTERIOPHAGE infection. The number of plaque-forming units in a given volume applied to the lawn can be used to calculate viral numbers in a suspension.
  2. a layer that forms on the surface of a tooth, composed of bacteria in an organic matrix (see BIOFILM). As the layer thickens, anaerobic respiration of the bacteria produces acids which dissolve the tooth enamel.

Plaque

Patches of scar tissue that form where the layer of yelin covering the nerve fibers is destroyed by the multiple sclerosis disease process.

plaque

, placque (plak)
2. Patch or small, differentiated area on body surface (e.g., skin, mucosa, or arterial endothelium) or on cut surface of an organ.
3. An area of clearing in a flat, confluent growth of bacteria or tissue cells.
[Fr. a plate]
References in periodicals archive ?
She noted that to date, research has not convincingly shown that infections and the ensuing inflammation are directly involved in the process of plaque instability and heart attack onset.
We stand on the shoulders of giants but in the case of sport most of the time we don't have a clue who these heroic female pioneers are," said the Blue Plaque Rebellion.
It's the second plaque, following on from the launch of the Purple Plaque campaign on International Women's Day 2018 which commemorated the late Assembly Member Val Feld.
It was only earlier this month that Vivian received an official apology from Cwm Taf University Health Board confirming the plaque was lost and offering to replace it with an exact replica of the original.
Dennis Bonnen, who is expected to lead the lower chamber next year, applauded Abbott's efforts and voiced his support for removing the plaque.
French maritime pine extract contains a complex mixture of compounds known as procyanidins and phenolic acids (5,6) that help slow the progression of arterial plaque. (4) How does it achieve this?
The cast plaques were created for the project by Leander Architectural, who also create the blue plaques for English Heritage.
In 2008, after I became the high commissioner, I was approached by prominent members of Pakistani community to put a plaque outside the mission.
The Charnwood Heritage Plaque scheme has been launched by the borough council to mark fascinating people, places and events in Charnwood's history.
According to a study conducted by the Society for Cardiovascular Angiography and Interventions, not only do the psoriasis treatments reduce the volume of the plaque, but also the plaque becomes less inflammatory over time harbouring fewer characteristics prone to rupture and cause a heart attack.
Novel Insights Into Human Carotid Atherosclerotic Plaque Composition and Blood Components