placental sulfatase deficiency

pla·cen·tal sul·fa·tase de·fi·cien·cy

an enzyme defect in the placenta that results in failure of conversion of 16α-hydroxydehydroepiandrosterone to estriol; women with this condition rarely enter into spontaneous labor.
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References in periodicals archive ?
So far, only one gene-linked anomaly related to abnormal labor has been discovered: placental sulfatase deficiency. This X-linked recessive disorder is extremely rare, occurring in only 1 in 2,000-6,000 pregnancies.