pituitary adenoma

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a benign epithelial tumor in which the cells form recognizable glandular structures or in which the cells are derived from glandular epithelium.
acidophilic adenoma in a classification system formerly used for pituitary adenomas, an adenoma whose cells stain pale pink with acid dyes; most adenomas that secreted excessive amounts of growth hormone were in this group
ACTH-secreting adenoma (adrenocorticotrophic hormone–secreting adenoma) corticotroph adenoma.
basophilic adenoma in a classification system formerly used for pituitary adenomas, an adenoma whose cells stain pale blue with basic dyes; most adenomas that secreted excessive amounts of adrenocorticotrophic hormone were in this group.
chromophobe adenoma (chromophobic adenoma) a pituitary adenoma composed of cells that lack acidophilic or basophilic granules; this is the same entity as the more precisely named null-cell a.
corticotrope adenoma (corticotroph adenoma) a pituitary adenoma made up predominantly of corticotrophs; excessive corticotropin secretion may cause Cushing's disease or Nelson's syndrome. Called also ACTH-secreting or adrenocorticotropic hormone–secreting adenoma and corticotropinoma.
endocrine-active adenoma a pituitary adenoma that secretes excessive amounts of a hormone; see prolactinoma, corticotroph adenoma, gonadotroph adenoma, growth hormone–secreting adenoma, and thyrotroph adenoma. Called also hyperfunctional or hyperfunctioning adenoma.
endocrine-inactive adenoma a pituitary adenoma that does not secrete excessive amounts of any hormone; many null-cell adenomas are of this type. Called also nonfunctional or nonfunctioning adenoma and nonsecreting or nonsecretory adenoma.
gonadotrope adenoma (gonadotroph adenoma) a rare type of pituitary adenoma made up of gonadotroph-like cells that secrete excessive amounts of follicle-stimulating hormone or luteinizing hormone or both; it may cause precocious puberty, visual disturbances, or hypogonadism.
growth hormone–secreting adenoma a pituitary adenoma made up of somatotroph-like cells that secrete excessive amounts of growth hormone; it may cause gigantism in children or acromegaly in adults. Called also somatotrope or somatotroph adenoma and eosinophilic adenoma.
hepatocellular adenoma a large, fleshy, hypervascular tumor of the liver occurring chiefly in women of childbearing age and associated with oral contraceptive use. It is composed of sheets of cells with areas of hemorrhage and necrosis and has a tendency to hemorrhage and rupture; it may become malignant.
Hürthle cell adenoma a benign hürthle cell tumor.
hyperfunctional adenoma (hyperfunctioning adenoma) endocrine-active adenoma.
lactotrope adenoma (lactotroph adenoma) prolactinoma.
liver cell adenoma hepatocellular adenoma.
nonfunctional adenoma (nonfunctioning adenoma) endocrine-inactive adenoma.
nonsecreting adenoma (nonsecretory adenoma) endocrine-inactive adenoma.
null-cell adenoma a pituitary adenoma whose cells give negative results on tests for staining and hormone secretion; although classically they were considered to be composed of sparsely granulated or degranulated (nonfunctioning) cells, some contain functioning cells and may be associated with a hyperpituitary state such as acromegaly or Cushing's syndrome. These tumors are often discovered clinically only when they have grown large and are pressing on surrounding structures. Called also chromophobic adenoma.
pituitary adenoma a benign neoplasm of the anterior pituitary gland; some contain hormone-secreting cells (endocrine-active adenomas) but some are not secretory (endocrine-inactive adenomas).
plurihormonal adenoma an endocrine-active adenoma that secretes more than one kind of hormone.
prolactin cell adenoma (prolactin-secreting adenoma) prolactinoma.
sebaceous adenoma hypertrophy or benign hyperplasia of a sebaceous (oil-secreting) gland.
adenoma seba´ceum nevoid hyperplasia of sebaceous glands, forming multiple yellow papules or nodules on the face. See also nevus.
somatotrope adenoma (somatotroph adenoma) growth hormone–secreting adenoma.
thyroid-stimulating hormone–secreting adenoma thyrotroph adenoma.
thyrotrope adenoma (thyrotroph adenoma) (TSH-secreting adenoma) a rare type of pituitary adenoma made up of thyrotroph-like cells that secrete excess thyrotropin and cause hyperthyroidism; called also thyroid stimulating hormone–secreting adenoma.
villous adenoma a large soft papillary polyp on the mucosa of the large intestine.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pi·tu·i·tar·y ad·e·no·ma

a benign neoplasm of the pituitary generally arising in the adenohypophysis.
Farlex Partner Medical Dictionary © Farlex 2012

pituitary adenoma

An adenoma of the pituitary gland, often of one of its functional cell types. It may produce excessive amounts of hormones such as prolactin, growth hormone, or adrenocorticotrophic hormone, or it may be clinically silent.
See also: adenoma
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
A case of thyrotropin secreting pituitary adenoma (TSHoma).
Cabergoline is a useful treatment model for pituitary adenomas. Pituitary surgery for macroadenomas may be needed in some patients.
Succinate dehydrogenase deficiency is rare in pituitary adenomas. Am J Surg Pathol.
Hence, in this research, we aimed to explore the effects of HULC on rat secreting pituitary adenoma GH3 cell line viability, migration, invasion, apoptosis, and hormone secretion, as well as miR-130b expression.
Pituitary adenoma was the most common diagnosis (14,193, 98.47%), among which nonfunctioning pituitary adenoma accounted for the largest proportion.
A radiologic score to distinguish autoimmune hypophysitis from non-secreting pituitary adenoma preoperatively.
According to recent literature, the endoscopic approach for pituitary adenomas can achieve a complete resection rate of 77%-96%27.
(10,11) Recent studies demonstrate that, although much more commonly seen with craniopharyngiomas, other entities such as pituitary adenomas, germ cell tumors, and malignant lymphomas can also demonstrate similar findings.
Case Sex Etiology Histology report 1 F AD Pituitary adenoma 2 F AD Pituitary adenoma 3 F AI Adrenal adenoma 4 F AI Adrenal adenoma 5 F AI Adrenal hyperplasia 6 M AI Adrenal hyperplasia 7 F AD Pituitary [mu]-adenoma 8 F AI Adrenal adenoma 9 F AI Adrenal adenoma Case Immune disease report 1 Graves' disease 2 Hashimoto thyroiditis 3 Psoriasis 4 Graves' disease 5 Systemic lupus erythematosus 6 Hashimoto thyroiditis 7 Rheumatoid arthritis 8 Myasthenia gravis 9 Horton disease M: male; F: female; AD: ACTH-dependent; AI: ACTH-independent.
However, in only two of eight patients with pituitary adenoma CgA level was mildly raised, which is expected since these tumors are not classically considered NETs.
Other lesions include fungal infections, pituitary adenoma, schwannoma, neurofibroma, carotid body paraganglioma, craniopharyngioma, arachnoid cyst, medulloblastoma and medulloepithelioma.
A 53-year-old woman presented to our emergency department with headache 7 days after an endoscopic endonasal skull base surgery with a transnasal transsphenoidal approach for pituitary adenoma. Clinical examination at the time of admission revealed normal findings; her Glasgow coma scale was 15 and all other vital signs were normal.