pirenzepine


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pirenzepine

A drug formerly used to cut secretion of acid by the stomach in the treatment of PEPTIC ULCER but now discontinued.

pirenzepine

a selective M1 cholinergic antagonist; used as an antiemetic in dogs.
References in periodicals archive ?
Pirenzepine is also an antimuscarinic drug which has been used in the treatment of myopia progression.
Success may be related to subject ethnicity and/or the technique to which it was being compared Pharmaceutical Anti-muscarinic drugs * Consistent data, inhibition of myopia shown when compared to placebos * Atropine found to be more effective than pirenzepine and cyclopentolate
Using the M1 receptor antagonist pirenzepine (PIR), the M3 receptor antagonist 4-diphenyl-acetoxy-N-methyl-piperidine methiodide (4-DAMP), and the cholinergic agonist carbachol, here we investigated the potential role of Ml and M3 mAChRs in mLTD induction and in increasing phosphorylated ERK levels in juvenile and adults rats.
Novartis to Introduce Pirenzepine Ophthalmic Gel 99
When investigators gave pirenzepine 25-100 mg/day to 120 patients with drooling because of clozapine, improvement was noted (Lancet 1995;346:1034).
Study participants received pirenzepine titrated up to 100 mg/day.
Comparison of pirenzepine, ranitidine, and pirenzepine-ranitidine combination for reducing preoperative gastric fluid acidity and volume in children.
Numerous anticholinergic medications, including glycopyrolate, scopolamine propantheline bromide, and pirenzepine, have been used in humans with varying results.
Comparison of two antimuscarinic drugs, pirenzepine and propantheline, on gastric acid secretion, salivary flow and heart rate in patients with duodenal ulcer disease.
Scientists developed a new eye gel after patients on pirenzepine noticed their vision changed as the drug temporarily altered the shape of their eyeball.
2% II-76 Taiwanese Researchers Introduces Thermosensitive Ophthalmic Drop II-76 Alcon Introduces Systane Lubricant Eye Drops II-76 Allergan Releases Restasis for Dry Eye Treatment II-76 Biosyntrx Launches BioTears II-76 Novartis to Introduce Pirenzepine Ophthalmic Gel II-76
Such research has now opened the door for extensive research into methods for myopia control, with interest in altering spectacle lens designs to reduce peripheral aberrations and the use of drugs such as Pirenzepine (an m1 anti-muscarinic) at the forefront.