In contrast to scopolamine, cholinergic drugs i.e rivastigmine, donepezil and
piracetam prevent the cholinergic neurons from the damages of AChE and hence can be used to prevent AD (Birks et al., 2000).
Piracetam (sun pharmaceuticals), scopolamine, normal saline, and ethanol were used.
VPA is the first-line AED in the treatment of myoclonic seizures, while LEV, CZP,
piracetam, ZNS, phenobarbital, TPM, and botulinum toxin are alternative therapeutic options.[6] MERRF is one of the most common causes of myoclonic seizures and tends to be more resistant to AEDs owing to mitochondrial disorders.[4],[7] There is a lack of specific therapies and recommendations regarding the treatment of myoclonic seizures resulting from MERRF.
Piracetam ameliorated oxygen and glucose deprivation-induced injury in rat cortical neurons via inhibition of oxidative stress, excitatory amino acids release and P53/Bax.
Double blind, placebo-controlled trial on the effect of
piracetam on breath-holding spells.
This idea is supported by the observation that
piracetam (the predecessor of LEV) is not associated with increased AB.
In one study, patients with age-associated memory impairment were given a high dose of
piracetam, a moderate dose, or a placebo, and were enrolled in memory training to observe the effects, if any, that
piracetam would have on memory.
Piracetam in the treatment of schizophrenia: implications for the glutamate hypothesis of schizophrenia.
[2,7,8] Several antioxidants, based on the free radical hypothesis of TD, have been studied for the therapeutic effects of TD, such as melatonin [6,9-11], vitamin [B.sub.6] [12,13], vitamin E [14,15], Ginkgo biloba (EGb) [4] and
piracetam. [16,17]
In a study of 52 young soldiers who were exposed to the noise of intense gunfre, 36.5% of subjects showed complete hearing recovery after treatment with steroids and
piracetam. But 68.4% of the patients who completely recovered began treatment within the first hour after acoustic trauma, which is quite a narrow window for patients to achieve.
Shafi et al., "Development of new method for simultaneous analysis of
piracetam and levetiracetam in pharmaceuticals and biological fluids: application in stability studies," BioMed Research International, vol.
However, LDA missed an important dehydration drug
piracetam, which is of high frequency in the dataset.
