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Related to piperidine: piperidine alkaloids


1. a compound from which are derived phenothiazine antipsychotics such as thioridazine hydrochloride and mesoridazine besylate.
2. One of a class of alkaloids containing a piperidine (1) moiety.
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Keywords: Piperidine, Pharmacological, Potentiometric titration, Absorption, Pharmacokinetics.
[50.] Panter KE, Keeler F: Piperidine alkaloids of poison hemlock
The mixture was heated to reflux for 24 h in the presence of a few drops of piperidine. After cooling to room temperature, solvents were removed by rotary evaporation.
The structure of m-iodobenzyltrozamicol (MIBT) (8) consists of a trozamicol skeleton, a compound with piperidine instead of cyclohexane in A ring, with an m-iodobenzyl group.
(i) DMF, 3,4- dihydroxybenzaldehyde, [K.sub.2]C[O.sub.3], refluxed for 24 h; (ii) CH[Cl.sub.3], cyanoacetic acid, piperidine, refluxed for 15 h.
Effects of piperidine and piperideine alkaloids from the venom of red imported fire ants, Solenopsis invicta Buren, on Pythium ultimum Trow growth in vitro and the application of piperideine alkaloids to control cucumber damping-off in the greenhouse.
The bromide 32 was subjected to palladium-catalyzed coupling with morpholine (33), stannous nitro reduction, condensation with benzoyl isothiocyanate, bromine promoted formation of the benzothiazole ring, and installation of the piperidine ring through intermediate 38.
A hardener, piperidine (Sigma-Aldrich, Australia), was used at a ratio of 100: 5 by weight for curing the epoxies.
In accordance with structural forms, the cited alkaloids are classified in diterpenoid alkaloids (14-O-acetylneoline, 14-O-veratroylpseudaconine, and hypaconitine), indole alkaloids (fumigaclavine C and isatin), indolonaphthyridine alkaloids (nigakinone), indoloquinazoline alkaloids (tryptanthin), isoquinoline alkaloids (berberine, boldine, cavidine, coptisine derivatives, EM012, papaverine, sanguinarine, sinomenine, tetrahydrocoptisine, and tetrandrine), phenanthroindolizidine alkaloids (NK-007 and W-8), piperidine alkaloids (piperine), purine alkaloids (caffeine), quinoline alkaloids (skimmianine), and quinolizidine alkaloids (matrine, oxymatrine, sophocarpine, and sophoridine).
(136) Rutgers proclaims, "Scientists have developed a proprietary method of extracting and purifying a novel type of piperidine flavan alkaloids from the leaves of Combretum micranthum (kinkeliba) and a procedure for the preparation of total piperidine flavan alkaloids (TPFA) that possess anti-diabetic properties." (137) Paralleling that of the previous two case studies, it does not appear that a specific traditional community, organization, or government within West Africa claimed the use of combretum micranthum as their intellectual property or specifically accused Rutgers of misappropriation.