The reduction of TLR4 gene expression during inflammatory conditions may be a mechanism that protects pineal cells
against extensive stimulation by endotoxins.
The supporting clinical studies that he cites demonstrated the effect of electromagnetic fields on the secretion and oncostatic action of melatonin, on pineal cells
, on bacteria and yeast proliferation, and on human immunoglobulin on the beta lymphocytes.
In experiments on hamsters, the antibody revealed thin nerve connections running from pineal cells
to the regions called the posterior commissure and the habenula.