pimozide


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pimozide

 [pi´mah-zīd]
an antipsychotic agent and antidyskinetic agent used in the treatment of gilles de la tourette's syndrome; administered orally.

pimozide

/pi·mo·zide/ an antipsychotic and antidyskinetic agent used in the treatment of Gilles de la Tourette's syndrome.

pimozide

(pĭm′ə-zīd′)
n.
An antipsychotic drug, C28H29F2N3O, used in the management of Tourette syndrome.

pimozide

[pim′əzīd]
an antipsychotic agent from the diphenylbutylpiperidine class.
indications It is prescribed for the suppression of motor and phonic tics associated with Gilles de la Tourette's syndrome.
contraindications It may cause electrocardiography changes, including a prolonged QT interval, and should not be given to patients with a congenital prolonged QT interval or a history of cardiac arrhythmias. It also may lower the seizure threshold of patients who are also taking an anticonvulsant drug. It should not be taken concurrently with drugs that are inhibitors of CYP3a4 (e.g., ketoconazole, erythromycin).
adverse effects Among the more serious adverse effects are extrapyramidal effects, persistent tardive dyskinesia, sedation, drowsiness, constipation, dry mouth, visual disturbances, and electrocardiograph changes.

pimozide

A long-acting phenothiazide antipsychotic drug of the diphenylbutylpiperidine group that is also used in the treatment of the GILLES DE LA TOURETTE'S SYNDROME. A brand name is Orap.

pimozide,

n brand name: Orap;
drug class: antipsychotic, antidyskinetic;
action: blocks dopamine effects on central nervous system;
uses: motor and phonic tics in Giles de la Tourette's syndrome.

pimozide

an antipsychotic agent in humans; used for its long-acting central antiemetic effect in dogs.
References in periodicals archive ?
In a controlled study of healthy volunteers, after paroxetine was titrated to 60 mg daily, co-administration of a single dose of 2 mg pimozide was associated with mean increases in pimozide AUC of 151% and [C.
1,2,16-19) Unlike pimozide and all other first-generation antipsychotics, the second-generation antipsychotics carry less risk of precipitating cardiac arrhythmias, especially prolonged QT intervals and torsades de pointes, extra-pyramidal syndromes, and tardive dyskinesias.
They identified one drug, Pimozide, an approved anti-psychotic drug, that restored the effects of steroids on NH cells.
Co-administration of cisapride, dofetilide, ergot alkaloids such as dihydroergotamine, ergotamine, ergometrine (ergonovine), and methylergometrine (methylergonovine); felodipine, levacetylmethadol (levomethadyl), lovastatin, methadone, oral midazolam, nisoldipine, pimozide, quinidine, simvastatin, and triazolam with ONMEL[TM] is contraindicated.
Synergetic effect of pimozide and thyrotropin releasing hormone on prolactin and thyrotropin release during the drying off of ewes.
Consumption of 6-8 glasses of grapefruit per day may raise levels of carbamazepine and pimozide.
CNS drugs: Alfentanil (oral), Buspirone, Dextromethorphan, Fentanyl (oral), Ketamine (oral), Lurasidone, Oxycodone, Pimozide, Quetiapine, Triazolam, Ziprasidone
Meanwhile, he benefited from aripiprazole and his behavioral symptoms resolved substantially without emerging an epileptic seizure, but we could not keep up the treatment because his parents requested the discontinuation of aripiprazole due to the severity of enuresis, thus, we ceased aripiprazole a week after the beginning and decided to switch to pimozide.
Pimozide attenuates free feeding: best score analysis reveals a motivational deficit.
Baslangicta pimozide ile cok iyi yanit alindi, hasta ilk kontrole geldiginde cok sevincli ve mutluydu: "Doktor, bugun yalnizca bir tane bocek gordum, cok azaldilar" dedi, oysa ben saf saf hastanin "doktooor
gariepinus, Viveiros et al (2), probaron diferentes protocolos con base en extracto hipofisiario de carpa y de Ciarias, mGnRHa con Pimozide y Ovaprim, de manera individual y en varias combinaciones.
Patients taking protease inhibitors should avoid pimozide, midazolam, triazolam, and St.