Acne vulgaris is a chronic, inflammatory disease of
pilosebaceous units, characterized by comedones, papules, pustules, nodules, and often scars.
The role of Demodex folliculorum, commensal mite of the
pilosebaceous follicle, has long been debated; it would promote inflammation by mechanical blockage of follicles.
Although acne is a disease of
pilosebaceous unit, it develops in the middle part of the sebaceous follicle channel and not in the sebaceous glands.
Yamada A, Saga K, Jimbow K: Acquired multiple
pilosebaceous cysts on the face having the histopathological features of steatocystoma multiplex and eruptive vellus hair cysts.
With regard to local synthesis, researchers argue that hair follicles are independent peripheral neuroendocrine organs capable of synthesizing relatively small amounts of cortisol in the
pilosebaceous unit located in the hair follicles in response to ACTH (D'Anna-Hernandez et al.
The hair follicle is divided into three segments, infundibulum extending from the surface opening of the follicle to the level of level of the opening of its sebaceous gland, it is part of the
pilosebaceous canal that is used as a route for the discharge of sebum; isthimus extending from the infundibulum to the level of insertion of arrector pili muscle.
Ectopic
pilosebaceous structure of the glans penis.
Androgenic hormones are present within the
pilosebaceous units of human skin have different inhibitory effects on the growth of some dermatophytes [3].
Epidermoid cyst, also known as sebaceous cyst or keratin cyst, is a dome-shaped lesion that arises from a ruptured
pilosebaceous follicle.
Pilosebaceous physiology in relation to hirsutism and acne.
Acne is a skin condition involving the
pilosebaceous follicles.
No alterations were found in the
pilosebaceous annexes.
