pilocarpine hydrochloride


Also found in: Dictionary, Thesaurus, Encyclopedia.

pilocarpine hydrochloride

a cholinergic derived from the leaves of the jaborandi tree and other species of Pilocarpus. It is used mainly in a topical ophthalmic preparation as a miotic to contract the pupil in cases of glaucoma. Pilocarpine is administered orally to increase saliva production in patients with xerostomia. Other consequences of cholinergic receptor stimulation include diaphoresis, bronchoconstriction, urinary urgency, nausea, and diarrhea.

pilocarpine hydrochloride

(pī″lă-kahr′pēn″)
C11H16N2O2·HCl; the hydrochloride of an alkaloid obtained from leaflets of Pilocarpus jaborandi and P. microphyllus.

Action/Uses

It is used as a cholinergic. Because it causes contraction of the pupil, it is used topically as a miotic, esp. in glaucoma.