A variety of nevus frequently encountered in Japan, nevus fusco-coeruleus ophthalmomaxillaris and its relation to
pigmentary changes in the eye.
However, we reached the diagnosis based on the patient's nephews having XLRS, the patient's history of low vision since childhood, and the detection of
pigmentary changes in the peripheral retina and vitreous changes on examination.
JS should be managed as early as possible before it results in serious complications such as decreased visual acuity due to
pigmentary retinopathy, optic coloboma, retinal dystrophy, retinitis, nephropathy, renal cyst, elevated liver enzymes, hyperpnea, and apnea.
In the 17th century, however, Malpighi had first published a scientific study on skin color, to be followed by John Hunter, who described the
pigmentary layer of the skin.
Pigmentary disorders were seen in 42 (14%) cases, of these, vitiligo was seen in 27 (9%) cases, melasma in 15 (5%).
Histologic findings in pigment dispersion syndrome and
pigmentary glaucoma.
However, similar immune mechanisms have been implicated in the pathogenesis of these cutaneous
pigmentary disorders.
The other cases developed complications like corneal opacity (Pug 1), exposure keratopathy leading to
pigmentary keratitis (Pugs 1, Spitz 1,Shih tzu 1) and kerato conjunctivitis sicca (Pug 1).
Family history was negative for similar dermatosis or other
pigmentary disorders.
Fundus findings include salt and pepper
pigmentary disturbance involving the periphery and posterior pole with normal vessels, RPE mottling and no intraretinal
pigmentary migration.
Minocycline-related
pigmentary disorders usually appear after several months of treatment and have been classified into four basic clinical patterns: (i) dark blue-black macules in acne scars or at sites of previous cutaneous inflammation; (ii) localised or diffuse hyperpigmented macules distant from the site of inflammation or infection, and affecting the shins or other sun-exposed areas; (iii) diffuse brown-grey discolouration (muddy skin syndrome) with a tendency to photo-aggravation; and (iv) hyperpigmentation of the vermilion area of lower lip.
Study on required energy to deagglomerate
pigmentary titanium dioxide in water--R.
