Genogroup I and II Picobirnaviruses
in Respiratory Tracts of Pigs
Sequence heterogeneity among human picobirnaviruses detected in a gastroenteritis outbreak.
Genome sequencing identifies genetic and antigenic divergence of porcine picobirnaviruses.
Molecular characterization of Picobirnaviruses from new hosts.
identified by molecular screening of diarrhea samples.
New picobirnaviruses and circular DNA viruses were identified and further characterized.
Picobirnaviruses are highly variable, double-stranded RNA viruses with a bisegmented genome.
To the Editor: Picobirnaviruses (family Picobirnaviridae) are nonenveloped, double-stranded RNA viruses of vertebrates with a bisegmented genome.
Recently, we identified picobirnaviruses in the respiratory tract of pigs in Asia, and this identification expanded the knowledge on the tropism and host range of picobirnaviruses (7).
Three clones showed picobirnaviruses, which are double-stranded RNA viruses with a segmented genome belonging to the family Picobirnaviridae (7).
Because picobirnaviruses have been identified only in fecal specimens, diagnostic PCRs for genogroup I and II picobirnaviruses specific for the RNA-dependent RNA polymerase (RdRp) gene (6,8,9) were performed on 60 respiratory tract swab specimens to determine whether picobirnaviruses are present in the porcine respiratory tract.
His research interest is genomic characterization of gastroenteritis viruses such as rotaviruses, noroviruses, and picobirnaviruses