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a cholinergic alkaloid having anticholinesterase activity, obtained from the dried ripe seed (Calabar bean) of Physostigma venenosum; used topically to produce miosis and to decrease intraocular pressure in glaucoma. It may also be applied parenterally to reverse the central nervous system effects produced by overdosage of anticholinergic drugs.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
An alkaloid of physostigma; it is a reversible inhibitor of the cholinesterases and prevents destruction of acetylcholine; used as a cholinergic agent, and experimentally to enhance the action of acetylcholine at any of its sites of liberation.
Farlex Partner Medical Dictionary © Farlex 2012
A crystalline alkaloid, C15H21N3O2, extracted from the Calabar bean, used in the form of its sulfate as a miotic and in the form of its salicylate as a cholinergic agent. Also called eserine.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
physostigmineA reversible antiacetylcholinesterase, used in Pts with Sx of an anticholinergic crisis Neurology Memory drug Physostigmine may improve working memory by ↑ efficiency and ↓ effort. See Working memory.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
A nonpolar carbamate antidote to anticholinergic compounds.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
physostigmineA CHOLINESTERASE inhibitor drug used to constrict the pupil of the eye and lower the pressure within the eye in GLAUCOMA. It is also used to treat poisoning with ANTICHOLINERGIC drugs. It is derived form the Calabar bean Physostigma venenosum . Also known as eserine.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
A reversible anticholinesterase drug used as a parasympathomimetic which, when used in the eye constricts the pupil. It may be used in solution of 0.25-1% or ointment 0.25-0.50% in the treatment of glaucoma, but because of its side-effects its usage is rare nowadays. It is sometimes combined with pilocarpine. Syn. eserine. See miotics; neostigmine; parasympathomimetic drug.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
Alkaloid used as a cholinergic agent, and experimentally to enhance action of acetylcholine at any of its sites of liberation.
Medical Dictionary for the Dental Professions © Farlex 2012