physical dependence


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dependence

 [de-pen´dens]
a need for something; sometimes used as a synonym for drug dependence.
chemical dependence (drug dependence) see drug dependence.
emotional dependence psychological dependence.
physical dependence (physiological dependence) drug dependence in which the drug is used to prevent withdrawal symptoms or in which it is associated with tolerance, or both.
psychoactive substance dependence drug dependence.
psychological dependence drug dependence in which the drug is used to obtain relief from tension or emotional discomfort; called also emotional dependence.
substance dependence drug dependence.

physical dependence

substance dependence in which there is evidence of tolerance, withdrawal, or both.

physical dependence

Substance abuse A physiologic state of neuro-adaptation to a specific opioid, characterized by a withdrawal syndrome if the drug is stopped or ↓ abruptly, or if an antagonist administered; PD may be relieved partly or completely by readministration of the substance. See Addiction, Tolerance.
References in periodicals archive ?
This article describes a cognitive-behavioral treatment approach designed specifically for problem drinkers with low levels of physical dependence on alcohol who choose to reduce their drinking.
There is widespread misunderstanding, both among health care professionals and society in general, about the differences between physical dependence and addiction.
In part they blamed "excessive and unrealistic concern about the danger of addiction," which doctors erroneously equated with tolerance and physical dependence.
Yet the Pennsylvania State Board of Medicine guideline says physicians should recognize that tolerance and physical dependence are normal consequences of sustained use of opioid analgesics and are not synonymous with addiction.
Concerns about physical dependence, tolerance, and addiction are barriers to the prescription of opioids by primary care physicians for patients with CNMP.
If addiction is driven by physical dependence on a chemical - in this case, nicotine - relapse should occur during withdrawal, which for nicotine typically lasts a few weeks.
Physicians, however, were concerned with the propensity of barbiturates to induce tolerance, physical dependence, drug interactions, and potential for a lethal withdrawal syndrome.
If by alcoholism one is referring to alcohol dependence, including significant physical dependence, studies indicate that few with this problem can adopt controlled drinking.
Okamoto M, Rao S, Walewski JL: Effect of dosing frequency on the development of physical dependence and tolerance to pentobarbital.
Patients may develop psychological or physical dependence on them, and tolerance to the drug develops rapidly, Dr.