physaliphorous

phys·a·liph·or·ous

(fis'ă-lif'ŏr-ŭs),
Having bubbles or vacuoles.
Synonym(s): physaliferous
[G. physallis, bladder, bubble, + phoros, bearing]

physaliphorous

(fĭs″ă-lĭf′ō-rŭs)
Pert. to a highly vacuolated cell present in a chordoma.
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References in periodicals archive ?
9) The hallmark cell of chordoma is the large physaliphorous cell with a central nucleus and numerous clear cytoplasmic vacuoles.
Microscopically, chordomas consist of nests or cords of physaliphorous cells separated by fibrous tissue septa and mucoid intercellular substance.
Histological examination revealed scattered physaliphorous cell nests with a lobular growth pattern.
T12-L2 laminectomy done, tumour decompressed and spine stabilized Microscopic examination revealed the classic physaliphorous type and the radiotherapy delivered and the patient got relief of pain.
Myxoid variant of chordoma is differentiated by its location in the sacrococcygeal region, base of skull, or the cervical spine and the presence of multinucleated, physaliphorous cells.
The epithelioid cells are slightly elongated, with associated large mucus-containing physaliphorous cells (figure 2).
The characteristic physaliphorous cells, showing abundant, pale, eosinophilic, vacuolated cytoplasm and mild nuclear atypia were noted in all cases (Figure 1, A).
Many of the tumour cells exhibit vacuolization of the cytoplasm resembling physaliphorous cells.
Histologically, they both show the characteristic physaliphorous cell; they stain for vimentin, S100, epithelial membrane antigen, and low molecular weight cytokeratins; and they are negative for high molecular weight keratins.
Physaliphorous cells were noted (figure 2), which stained strongly for S-100, epithelial membrane antigen (EMA) and, focally, AE1-3 cytokeratin.
On microscopy, smears were cellular comprising of round to pleomorphic cells arranged in clusters, monolayered sheet and scattered singly and classic mono and bi nucleated physaliphorous cells.
Histologically, chordoma is composed of 2 cell populations, multivacuolated physaliphorous cells (Figure 9, A) and pink epithelioid cells (Figure 9, B), arranged in anastomosing cords in a myxoid or occasionally cartilaginous matrix, the latter typically seen in chondroid chordomas occurring predominantly in the skull base.