phthalates


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phthalates

(thăl′ātes)
Chemical compounds used to improve the flexibility of plastics. In health care, phthalates are used in devices such as intravenous tubing. They are also used in numerous consumer goods, including nail polish, soaps, shampoos, and vinyl, among many others. Some evidence suggests these compounds may have carcinogenic, endocrine disruptive, or other toxic effects on adults or the developing fetus.
References in periodicals archive ?
Exposure to phthalates and phenols during pregnancy and offspring size at birth.
At NPE2015, Arkema launched the Vikoplast soy-based plasticizers for consumer and industrial applications as direct replacements for phthalates. They reportedly perform similarly in terms of physical properties, with one key difference: The same level of flexibility and performance can be achieved by using 20-30% less Vikoplast, according to Arkema.
When you read the labels of natural skincare, beauty, and other personal care products, many of them include the claim that they are "phthalate-free." But many people don't know what phthalates are or whether it's really necessary to avoid them.
* DOTP (Di-octyl terephthalate)--a distant but harmless relative of DOP the classified phthalate
Bousquet et al., "Identification and quantification of 14 phthalates and 5 non-phthalate plasticizers in PVC medical devices by GC-MS," Journal of Chromatography B, vol.
Considering the fact that phthalates also have a role in reducing the male fertility by causing seminife-rous tubules atrophy and seminiferous epithelial cells disintegration, it is suggested that the mechanism be-hind it is oxidative stress in testes of adult rats.17 The physiological production of ROS is aimed to destroy the external threatening agents, but when produced in excess, the defense mechanisms of the cells are them-selves compromised leading to oxidative stress and cell damage.18 The oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and the biological system's ability to readily detoxify the reactive intermediates or to repair the re-sultant damage.19
Almost all perfumed products including air fresheners, insect repellents, deodorants, detergents, lipstick, and nail polish contain phthalates. Many medical devices like IV drip bags and tubes are full of phthalates.
Air exposures to phthalates were high but below limits set for industrial workers.
Some phthalates have been linked to endocrine disruption and developmental and reproductive toxicity so preventing harmful ones ending up in toys and other childcare items is a priority.
The researchers found no associations between the other two phthalates and child IQ.
"Phthalates are suspected carcinogens and are known to disturb the endocrine system in both humans and animals."
Phthalates (pronounced thol-htes) are a type of chemical used in many consumer products, including cheaper, mass-produced sex toys.