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Related to phrynoderma: keratosis pilaris


1. hypertrophy of the horny layer of the skin, or any disease characterized by it.
2. hypertrophy of the cornea. adj., adj hyperkeratot´ic.
epidermolytic hyperkeratosis a hereditary autosomal dominant form of ichthyosis, present at birth. Characteristics include generalized redness of the skin and severe hyperkeratosis with small, hard wartlike scales over the entire body, accentuated in areas that flex or bend and sometimes involving the palms and soles. In infancy and childhood, there are recurrent bullae, most often on the lower limbs.
follicular hyperkeratosis a skin condition characterized by excessive development of keratin in hair follicles, resulting in rough, cone-shaped, elevated papules, the openings of which are often closed with a white plug of encrusted sebum. Deficiencies of vitamins A and E, B complex vitamins, and essential fatty acids have all been implicated in the etiology. Called also phrynoderma.
hyperkeratosis lenticula´ris per´stans an autosomal dominant skin disorder, usually occurring in the third or fourth decade of life, characterized by pink, red, or yellow to brown scaly papules on the lower leg and back of the foot, and sometimes on the trunk, thigh, arm, back and palm of the hand, or sole of the foot.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A follicular hyperkeratotic eruption thought to be due to deficiency of vitamin A.
Synonym(s): toad skin
[G. phrynos, toad, + derma, skin]
Farlex Partner Medical Dictionary © Farlex 2012


A follicular hyperkeratotic eruption thought to be due to deficiency of vitamin A.
[G. phrynos, toad, + derma, skin]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Good to excellent response to Vitamin A therapy suggest that Phrynoderma is a nutritional deficiency state..
This study shows that the simultaneous use of Vitamin A, in the oral dose of 50,000 IU, given daily for 8 weeks, along with daily topical salicylic acid 3% and tretinoin 0.025%, gives good results in the treatment of phrynoderma, and compared with this, the results given by oral intake of safflower oil or Vitamin E along with topical salicylic acid 3% and tretinoin 0.025% is inferior.
Further studies are required to know the exact pathogenesis and the role played by different nutrients in the development of Phrynoderma, so that exact etiological factors can be elucidated.
Phrynoderma: A condition due to vitamin deficiency.
Vitamin A deficiency phrynoderma: due to malabsorption and inadequate diet.
Phrynoderma: A manifestation of Vitamin A deficiency?
Bypass phrynoderma. Vitamin A deficiency associated with bowel-bypass surgery.
The etiology of phrynoderma. Ind Med Gaz 1947; 82:16-20.
Phrynoderma and perforating folliculitis due to vitamin A deficiency in diabetes.
Phrynoderma and some associated changes in blood lipids.
Phrynoderma: Clinical and Biochemical Investigations.